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Now showing items 201-210 of 542
Practice implications of an antimicrobial stewardship intervention in a tertiary care teaching hospital, Qatar
(
World Health Organization
, 2019 , Article)
Background: Antibiotic misuse is a worldwide public health problem and has been associated with increased morbidity, length of hospital stay, mortality, healthcare costs, and most importantly antibiotic resistance. Aims: ...
An original transformer and switched-capacitor (T & SC)-based extension for DC-DC boost converter for high-voltage/low-current renewable energy applications: Hardware implementation of a new T & SC boost converter
(
MDPI AG
, 2018 , Article)
In this article a new Transformer and Switched Capacitor-based Boost Converter (T & SC-BC) is proposed for high-voltage/low-current renewable energy applications. The proposed T & SC-BC is an original extension for ...
Administration error of benzathine penicillin G in a Saudi male
(
Wiley-Blackwell
, 2019 , Article)
Background
Benzathine penicillin G is indicated for intramuscular (IM ) administration. There have been reports of unintentional intravenous (IV ) administration, which has been associated with cardiorespiratory arrest ...
Clinical and Pharmacokinetic Outcomes of Peak–Trough-Based Versus Trough-Based Vancomycin Therapeutic Drug Monitoring Approaches: A Pragmatic Randomized Controlled Trial
(
Springer-Verlag France
, 2019 , Article)
Background
Vancomycin therapeutic drug monitoring (TDM) is based on achieving 24-h area under the concentration–time curve to minimum inhibitory concentration cure breakpoints (AUC24/MIC). Approaches to vancomycin TDM ...
Clinical and Economic Analysis of Morphine Versus Fentanyl in Managing Ventilated Neonates With Respiratory Distress Syndrome in the Intensive Care Setting
(
Excerpta Medica Inc.
, 2019 , Article)
Purpose: Morphine and fentanyl opioids are common analgesic agents for consideration in the neonatal intensive care unit (NICU) for neonates with respiratory distress syndrome (RDS) and undergoing mechanical ventilation ...
Multimorbidity and emergency department visits by a homeless population: a database study in specialist general practice.
(
Royal College of General Practitioners
, 2019 , Article)
Estimating healthcare needs of the homeless is associated with challenges in identifying the eligible population. To explore the demographic characteristics, disease prevalence, multimorbidity, and emergency department ...
Taxane formulations: From plant to clinic
(
Springer International Publishing
, 2017 , Book chapter)
Taxanes including paclitaxel and docetaxel are highly active against many types of cancers. The main obstacle with developing delivery systems of taxanes is their poor water solubility. In this chapter, taxanes were reviewed ...
Clinical Pharmacokinetics and Drug Interactions of Doravirine
(
Springer-Verlag France
, 2018 , Article Review)
Doravirine is a new HIV-1 non-nucleoside reverse transcriptase inhibitor that has demonstrated a good efficacy and safety profile in clinical trials. It has a therapeutic profile that makes it an attractive option for ...
Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
(
NLM (Medline)
, 2018 , Article)
Cardiovascular diseases are the leading cause of death worldwide. One in three cases of heart failure is due to dilated cardiomyopathy. The Na+/H+ exchanger isoform 1 (NHE1), a multifunctional protein and the key pH regulator ...
Pass-fail decisions for borderline performers after a summative objective structured clinical examination
(
American Association of Colleges of Pharmacy
, 2019 , Article)
Objective. To determine what expert assessors value when making pass-fail decisions regarding pharmacy students based on summative data from objective structured clinical examinations (OSCE), and to determine the reliability ...