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Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy
(
Public Library of Science
, 2015 , Article)
Enhanced expression and activity of the Na+/H+ exchanger isoform 1 (NHE1) has been implicated in cardiomyocyte hypertrophy in various experimental models. The upregulation of NHE1 was correlated with an increase in osteopontin ...
Important steps for introducing interprofessional education into health professional education
(
Elsevier
, 2016 , Article)
Interprofessional education (IPE) engages students from different healthcare professions for learning with, from and about each other to improve collaboration and quality of care. Recognizing the complexity of designing ...
The prevalence of novel psychoactive substances (NPS) use in non-clinical populations: a systematic review protocol
(
BioMed Central
, 2016 , Article)
Background
Novel psychoactive substances (NPS) are new narcotic or psychotropic drugs that are not controlled by the United Nations drug convention that may pose a serious public health threat due to their wide availability ...
Drug-Related Hospital Visits and Admissions Associated with Laboratory or Physiologic Abnormalities-A Systematic-Review
(
Public Library of Science
, 2013 , Article)
Countless studies have demonstrated that many emergency-room visits and hospital admissions are drug-related and that a significant proportion of these drug-related visits (DRVs) are preventable. It has not been previously ...
Oral PTCTS (Particulated Transialidase) Removes Serum Microparticles and Decreases Inflammation in Atherosclerotic Plaques of Rabbits
(
Scientific Research Publishing
, 2015 , Article)
Background: Previous studies showed that atherosclerotic plaque vulnerability was related with microparticles (MPs)-vesicles larger than 100 nm, which released MMP9 collagenase. In our pre- vious study, intramuscular ...
Heme oxygenase (HO)-1 induction prevents Endoplasmic Reticulum stress-mediated endothelial cell death and impaired angiogenic capacity
(
Elsevier
, 2016 , Article)
Most of diabetic cardiovascular complications are attributed to endothelial dysfunction and impaired angiogenesis. Endoplasmic Reticulum (ER) and oxidative stresses were shown to play a pivotal role in the development of ...
Economic Opportunity: Brand Drugs vs. Generic Drugs
(2018 , Presentation)
Outlines:
* Pharmaceutical markets in the Middle East region are attractive
*The high spending on branded drugs is unsustainable
*Publicly funded health systems – increased pressure to reduce rising drug budgets
*Originator ...
Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury
(
Hindawi
, 2017 , Article)
Diabetic nephropathy (DN) is the leading cause of end stage renal disease worldwide. Increased glucose flux into the aldose reductase (AR) pathway during diabetes was reported to exert deleterious effects on the kidney. ...
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells
(
MDPI AG
, 2019 , Article)
Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ...
Perception of community pharmacy personnel towards patient counseling and continuing pharmacy education programs in Aden, Yemen
(
Journal of Clinical and Diagnostic Research
, 2018 , Article)
© 2018, Journal of Clinical and Diagnostic Research. All rights reserved. Introduction: Patient counseling is a major component of pharmaceutical care, especially in community pharmacy settings. However, most community ...