• Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages. 

      Corbett, Kizzmekia S; Moin, Syed M; Yassine, Hadi M; Cagigi, Alberto; Kanekiyo, Masaru; ... more authors ( American Society for Microbiology , 2019 , Article)
      Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by current vaccines. ...
    • Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. 

      Kanekiyo, Masaru; Joyce, M Gordon; Gillespie, Rebecca A; Gallagher, John R; Andrews, Sarah F; ... more authors ( Nature Research , 2019 , Article)
      The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy. This necessitates new approaches that provide ...
    • Nanotechnology in medicine – our experiences 

      Geskovski, Nikola; Mraiche, Fatima; Yalcin, Huseyin C.; Gorachinov, Filip; Moustafa, Diala A.; ... more authors ( Macedonian Pharmaceutical Association , 2022 , Article)
      The success of design criteria for long-circulating drug delivery systems to support membrane receptor-ligand interaction and internalization has been limited and there is a need to develop smarter approaches for efficient ...
    • Reduced Cardiotoxicity of Ponatinib-Loaded PLGA-PEG-PLGA Nanoparticles in Zebrafish Xenograft Model. 

      Al-Thani, Hissa F; Shurbaji, Samar; Zakaria, Zain Zaki; Hasan, Maram H; Goracinova, Katerina; ... more authors ( MDPI , 2022 , Article)
      Tyrosine kinase inhibitors (TKIs) are the new generation of anti-cancer drugs with high potential against cancer cells' proliferation and growth. However, TKIs are associated with severe cardiotoxicity, limiting their ...
    • Zebrafish as a Model for Anticancer Nanomedicine Studies. 

      Al-Thani, Hissa F; Shurbaji, Samar; Yalcin, Huseyin C ( MDPI , 2021 , Article Review)
      Nanomedicine is a new approach to fight against cancer by the development of anticancer nanoparticles (NPs) that are of high sensitivity, specificity, and targeting ability to detect cancer cells, such as the ability of ...