Show simple item record

AuthorMarei, Hany E.
AuthorAlthani, Asmaa
AuthorSuhonen, Jaana
AuthorEl Zowalaty, Mohamed E.
AuthorAlbanna, Mohammad A.
AuthorCenciarelli, Carlo
AuthorWang, Tengfei
AuthorCaceci, Thomas
Available date2016-07-20T11:08:01Z
Publication Date2016-07-01
Publication NameJournal of Cellular Physiologyen_US
CitationMarei, H. E., Althani, A., Suhonen, J., El Zowalaty, M. E., Albanna, M. A., Cenciarelli, C., Wang, T. and Caceci, T. (2016), Common and Rare Genetic Variants Associated With Alzheimer's Disease. J. Cell. Physiol., 231: 1432–1437. doi: 10.1002/jcp.25225
AbstractAlzheimer's disease (AD) is one of the most devastating disorders. Despite the continuing increase of its incidence among aging populations, no effective cure has been developed mainly due to difficulties in early diagnosis of the disease before damaging of the brain, and the failure to explore its complex underlying molecular mechanisms. Recent technological advances in genome-wide association studies (GWAS) and high throughput next generation whole genome, and exome sequencing had deciphered many of AD-related loci, and discovered single nucleotide polymorphisms (SNPs) that are associated with altered AD molecular pathways. Highlighting altered molecular pathways linked to AD pathogenesis is crucial to identify novel diagnostic and therapeutic AD targets.
SponsorBRC, QU
SubjectGenetic varients
SubjectAlzheimer's disease
Subjectrare varients
Subjectcommon varients
TitleCommon and Rare Genetic Variants Associated With Alzheimer's Disease
Issue Number7
Volume Number231

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record