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    Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq

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    Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq.pdf (323.8Kb)
    Date
    2015-02
    Author
    Dujaili, Juman Abdulelah
    Sulaiman, Syed Azhar Syed
    Hassali, Mohamed Azmi
    Awaisu, Ahmed
    Blebil, Ali Qais
    Bredle, Jason M.
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    Abstract
    Summary ObjectivesTo determine how tuberculosis (TB) treatment affects the health-related quality of life (HRQL) of patients with pulmonary TB and to identify the predictors of favourable TB treatment outcomes in Baghdad, Iraq. MethodsThe Functional Assessment of Chronic Illness Therapy – Tuberculosis (FACIT-TB), a new TB-specific quality of life instrument derived from the internationally recognized FACIT measurement system for the assessment of HRQL, was administered. The mean total and subscale scores of the FACIT-TB at baseline, end of the intensive phase, and end of TB treatment were compared. ResultsAfter the 2-month intensive phase, physical well-being, functional well-being, and the overall total scores were significantly increased (p<0.01). Furthermore, at completion of TB treatment, there were significant improvements in the overall HRQL as indicated by the FACIT-TB total score and all subscales, except social and economic well-being and spiritual well-being. In a direct logistic regression model, only the FACIT-TB total score made a statistically significant contribution towards predicting the likelihood that a patient would have a favourable TB treatment outcome. ConclusionsTherapeutic intervention had a positive impact on patient HRQL. We conclude that FACIT-TB is a reliable tool to monitor HRQL during the course of TB treatment.
    URI
    http://www.sciencedirect.com/science/article/pii/S1201971214017214
    DOI/handle
    http://dx.doi.org/10.1016/j.ijid.2014.12.004
    http://hdl.handle.net/10576/4762
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