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Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity
(
Elsevier
, 2017 , Article)
Abstract Epigallocatechin 3-gallate (EGCG) from green tea may reduce plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation. We hypothesized that EGCG would ...
Predictors of Continued Breastfeeding at One Year among Women Attending Primary Healthcare Centers in Qatar: A Cross-Sectional Study
(
MDPI
, 2018 , Article & Book chapter)
The number of babies in Qatar being exclusively breastfed is significantly lower than the global target set by the World Health Organization. The purpose of this study was to assess knowledge, attitude, and practice (KAP), ...
Dietary patterns associated with hypertension risk among adults in Thailand: 8-year findings from the Thai Cohort Study
(
Cambridge University Press (CUP)
, 2018 , Article)
Dietary intake is a leading risk factor for hypertension. We aimed to assess longitudinal associations between overall dietary patterns and incident hypertension among adults in Thailand. Prospective large Thai Cohort Study ...
Chitosan gold nanoparticles for detection of amplified nucleic acids isolated from sputum
(
Elsevier
, 2017 , Article)
A platform for nucleic acid detection employing chitosan and chitosan coated gold nanoparticles (AuNPs)
was developed. Mycobacterium tuberculosis (MTB) was used as a model target. MTB DNA was extracted
from sputum using ...
Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids
(
Elsevier
, 2015 , Article)
We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydroxyeicosatetraenoic acids (HETEs), contribute to diabetic retinopathy (DR) via NADPH oxidase (NOX) and disruption of the balance in retinal ...
Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa
(
Taylor & Francis
, 2017 , Article)
Over the past two decades, studies have documented the wide-range anti-cancer effects of Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active ingredient, has also been extensively studied ...
Adipose tissue dysfunction in cancer cachexia
(
Wiley Periodicals, Inc.
, 2018 , Article)
Cancer cachexia is a complex disorder that is driven by inflammation and metabolic imbalances, resulting in extreme weight loss. Adipose tissue, a main player in cancer cachexia, is an essential metabolic and secretory ...
Incidence and Prevalence of Pressure Injuries in Adult Intensive Care Patients: A Systematic Review and Meta-Analysis.
(
Lippincott, Williams & Wilkins
, 2018 , Article Review)
To systematically assess the incidence and prevalence of pressure injuries in adult ICU patients and the most frequently occurring pressure injury sites. MEDLINE, Embase, the Cochrane Library, and Cumulative Index to Nursing ...
Common and Rare Genetic Variants Associated With Alzheimer's Disease
(
WILEY PERIODICALS, INC.
, 2016 , Article)
Alzheimer's disease (AD) is one of the most devastating disorders. Despite the continuing increase of its incidence among aging populations, no effective cure has been developed mainly due to difficulties in early diagnosis ...
Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
(
Plos One
, 2017 , Article)
Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. Over the past years, several studies have reported the association of missense mutations in the ...