تصفح Biomedical Sciences حسب الموضوع "VSMC"
السجلات المعروضة 1 -- 3 من 3
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Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients.
( Hindawi Publishing Corporation , 2018 , Article)Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by an exacerbated fibrotic response. Although molecular and cellular determinants involved in the onset and progression of this devastating disease ... -
Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
( Frontiers Media , 2018 , Article Review)Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ... -
Reduced vasorin enhances angiotensin II signaling within the aging arterial wall
( Impact Journals , 2018 , Article)The glycosylated protein vasorin physically interacts with the transforming growth factor-beta1 (TGF-β1) and functionally attenuates its fibrogenic signaling in the vascular smooth muscle cells (VSMCs) of the arterial wall. ...