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    Electrospun alginate nanofibres impregnated with silver nanoparticles: Preparation, morphology and antibacterial properties

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    Date
    2017-06-01
    Author
    Mokhena, T.C.
    Luyt, A.S.
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    Abstract
    Abstract Silver nanoparticles are amongst the most valuable nanoparticles with interesting properties, such as a non-toxic nature and high antibacterial efficiency, making them applicable for tissue scaffold, protective clothing and wound dressing. In this study, silver nanoparticles (AgNPs) have been synthesized using chitosan as reducing and stabilizing agent. The formation of silver nanoparticles was confirmed by UV-vis, and the TEM showed that different shapes were obtained depending on the heating duration. The chitosan/AgNPs was coated onto an electrospun alginate membrane to produce stable polyelectrolyte complex (PEC) nanofibre composites with high antibacterial efficiency. These composites were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). AgNPs were successfully impregnated into the PEC nanofibre composite, while there was complexation between the electrospun alginate and the chitosan/AgNPs composite. PEC demonstrated a good antibacterial activity against both gram negative and gram positive bacteria with acceptable water vapour transmission within the range required for the treatment of injuries or wounds.
    URI
    http://www.sciencedirect.com/science/article/pii/S0144861717301984
    DOI/handle
    http://dx.doi.org/10.1016/j.carbpol.2017.02.068
    http://hdl.handle.net/10576/5334
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    • Center for Advanced Materials Research [‎436 ‎ items ]

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