Analysis of spatial data with a nested correlation structure
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Spatial statistical analyses are often used to study the link between environmental factors and the incidence of diseases. In modelling spatial data, the existence of spatial corre- lation between observations must be considered. However, in many situations, the exact form of the spatial correlation is unknown. This paper studies environmental factors that might inﬂu- ence the incidence of malaria in Afghanistan.We assume that spatial correlation may be induced by multiple latent sources. Our method is based on a generalized estimating equation of the marginal mean of disease incidence, as a function of the geographical factors and the spatial correlation. Instead of using one set of generalized estimating equations, we embed a series of generalized estimating equations, each reﬂecting a particular source of spatial correlation, into a larger system of estimating equations. To estimate the spatial correlation parameters, we set up a supplementary set of estimating equations based on the correlation structures that are induced from the various sources. Simultaneous estimation of the mean and correlation parameters is performed by alternating between the two systems of equations.
- Mathematics, Statistics & Physics [133 items ]