Biomedical Research Center
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Biomedical Research Center Research [365 items ]
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Bio-vehicles of cytotoxic drugs for delivery to tumor specific targets for cancer precision therapy
( Elsevier , 2021 , Article Review)Abnormal structural and molecular changes in malignant tissues were thoroughly investigated and utilized to target tumor cells, hence rescuing normal healthy tissues and lowering the unwanted side effects as non-specific ... -
High Endurance Elite Athletes Show Age-dependent Lower Levels of Circulating Complements Compared to Low/Moderate Endurance Elite Athletes
( Frontiers Media , 2021 , Article)Introduction: Aerobic exercise activates the complement system in the peripheral blood. However, the effect of age and high intensity endurance training on the levels of circulating complements and sassociated inflammatory ... -
Investigation of the effect of anticoagulant usage in the flow diverter stent treatment of the patient-specific cerebral aneurysm using the Lagrangian coherent structures
( Elsevier , 2021 , Article)Anticoagulants are prescribed to the flow diverter treated patients to diminish the risk of embolism in the arteries. In the present study, digital subtraction angiography images of a 49-year-old female patient with a left ... -
A review of smart sensors coupled with Internet of Things and Artificial Intelligence approach for heart failure monitoring
( Springer Nature , 2021 , Article)Over the last decade, there has been a huge demand for health care technologies such as sensors-based prediction using digital health. With the continuous rise in the human population, these technologies showed to be ... -
SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy
( Elsevier , 2021 , Article)BackgroundReinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been documented, raising public health concerns. SARS-CoV-2 reinfections were assessed in a cohort of antibody-positive persons ... -
mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar
(2021 , Article)The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants in a ... -
Epidemiological impact of prioritising SARS-CoV-2 vaccination by antibody status: Mathematical modelling analyses
( BMJ Publishing Group , 2021 , Article)Background Vaccines against SARS-CoV-2 have been developed, but their availability falls far short of global needs. This study aimed to investigate the impact of prioritising available doses on the basis of recipient ... -
SARS-CoV-2 seroprevalence in the urban population of Qatar: An analysis of antibody testing on a sample of 112,941 individuals
( Elsevier , 2021 , Article)The study objective was to the assess level of detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the urban population of Qatar. Antibody testing was performed on residual blood specimens ... -
SARS-CoV-2 Infection Is at Herd Immunity in the Majority Segment of the Population of Qatar.
( Oxford University Press , 2021 , Article)Qatar experienced a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic that disproportionately affected the craft and manual worker (CMW) population, who comprise 60% of the total population. This study ... -
Halloysite nanotubes and halloysite-based composites for biomedical applications
( Elsevier , 2021 , Article)Novel biomaterials for diagnostics and therapeutics of biomedical issues have been considered using biomedical science and health care. Halloysite nanotubes (HNTs) are naturally occurring aluminosilicate clay. Because of ... -
Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells
( Elsevier , 2021 , Article)Cardiovascular disease is one of the leading causes of mortality worldwide. Cardiac tissue engineering strategies focusing on biomaterial scaffolds incorporating cells and growth factors are emerging as highly promising ... -
Role of Inflammatory Cytokines, Growth Factors and Adipokines in Adipogenesis and Insulin Resistance
( Springer , 2021 , Article Review)Obesity, manifested by increased adiposity, represents a main cause of morbidity in the developed countries, causing increased risk of insulin resistance and type 2 diabetes mellitus. Recruitment of macrophages and activation ... -
Characterization of MXene as a Cancer Photothermal Agent Under Physiological Conditions
( Frontiers Media , 2021 , Article)A growing interest has recently emerged in the use of nanomaterials in medical applications. Nanomaterials, such as MXene, have unique properties due to their 2D ultra-thin structure, which is potentially useful in cancer ... -
Numerical Investigation of the Fetal Left Heart Hemodynamics During Gestational Stages
( Frontiers Media , 2021 , Article)Flow-driven hemodynamic forces on the cardiac tissues have critical importance, and have a significant role in the proper development of the heart. These mechanobiological mechanisms govern the cellular responses for the ... -
Regular, Intense Exercise Training as a Healthy Aging Lifestyle Strategy: Preventing DNA Damage, Telomere Shortening and Adverse DNA Methylation Changes Over a Lifetime.
( Frontiers Media , 2021 , Article)Exercise training is one of the few therapeutic interventions that improves health span by delaying the onset of age-related diseases and preventing early death. The length of telomeres, the 5'-TTAGGG -3' tandem repeats ... -
Predictive Biomarkers of Intensive Care Unit and Mechanical Ventilation Duration in Critically-Ill Coronavirus Disease 2019 Patients.
( Frontiers Media , 2021 , Article)Detection of early metabolic changes in critically-ill coronavirus disease 2019 (COVID-19) patients under invasive mechanical ventilation (IMV) at the intensive care unit (ICU) could predict recovery patterns and help in ... -
Computational Analysis of Wall Shear Stress Patterns on Calcified and Bicuspid Aortic Valves : Focus on Radial and Coaptation Patterns
( MDPI , 2021 , Article)Calcification and bicuspid valve formation are important aortic valve disorders that disturb the hemodynamics and the valve function. The detailed analysis of aortic valve hemodynamics would lead to a better understanding ... -
Chromosome aberrations and fertility disorders in domestic animals
( Annual Reviews Inc. , 2016 , Article Review)The association between chromosomal abnormalities and reduced fertility in domestic animals is well recorded and has been studied for decades. Chromosome aberrations directly affect meiosis, gametogenesis, and the viability ... -
A Non-Reciprocal Autosomal Translocation 64,XX, t(4;10)(q21;p15) in an Arabian Mare with Repeated Early Embryonic Loss
( Blackwell Publishing Ltd , 2016 , Article)Contents: Balanced autosomal translocations are a known cause for repeated early embryonic loss (REEL) in horses. In most cases, carriers of such translocations are phenotypically normal, but the chromosomal aberration ...
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