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Architecture of Viral RNA Helicases; HCV Helicase as Antiviral Target
(2018 , Article Review)
Around 80% of known viruses comprise of RNA and its specific RNA helicases that are vital for most RNA metabolism
includingpre-mRNA splicing, translation,initiation, and ribosome biogenesis. The viral helicases are crucial ...
Advances in osteobiologic materials for bone substitutes.
(
John Wiley and Sons
, 2018 , Article Review)
A significant challenge in the current orthopedics is the development of suitable osteobiologic materials that can replace the conventional allografts, autografts, and xenografts and thereby serve as implant materials as ...
Novel CD44-downstream signaling pathways mediating breast tumor invasion
(
Ivyspring International Publisher
, 2018 , Article Review)
CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell
and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways,
including ...
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...
Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression.
(
Frontiers Media
, 2018 , Article Review)
Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein-Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, ...
The Role of Epstein-Barr Virus in Cervical Cancer: A Brief Update.
(
Frontiers Media
, 2018 , Article Review)
Epstein-Barr virus (EBV) belongs to the group of gamma-herpes viruses and was the first recognized human oncovirus. EBV is responsible for infectious mononucleosis and multiple lymphoid and epithelial malignancies including ...
Potential of Stem Cell-Based Therapy for Ischemic Stroke.
(
Frontiers Media
, 2018 , Article Review)
Ischemic stroke is one of the major health problems worldwide. The only FDA approved anti-thrombotic drug for acute ischemic stroke is the tissue plasminogen activator. Several studies have been devoted to assessing the ...
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
(
Frontiers Medi
, 2018 , Article Review)
The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent
of infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of
individuals worldwide and has been linked to ...