Browsing Laboratory Animal Research Center by Type "Article Review"

Now showing items 1-20 of 31

    • Applications of polydopaminic nanomaterials in mucosal drug delivery 

      Takwa, Bedhiafi; Idoudi, Sourour; Alhams, Areej Ali; Fernandes, Queenie; Iqbal, Heba; ... more authors ( Elsevier , 2023 , Article Review)
      Polydopamine (PDA) is a biopolymer with unique physicochemical properties, including free-radical scavenging, high photothermal conversion efficiency, biocompatibility, biodegradability, excellent fluorescent and theranostic ...

    • Association of genes with phenotype in autism spectrum disorder. 

      Nisar, Sabah; Hashem, Sheema; Bhat, Ajaz A; Syed, Najeeb; Yadav, Santosh; ... more authors ( Impact Journals , 2019 , Article Review)
      Autism spectrum disorder (ASD) is a genetic heterogeneous neurodevelopmental disorder that is characterized by impairments in social interaction and speech development and is accompanied by stereotypical behaviors such as ...

    • Cadmium Toxicity: Oxidative Stress, Inflammation and Tissue Injury 

      Das, Sandra Concepcion; Al-Naemi, Hamda A. ( Scientific Research Publishing , 2019 , Article Review)
      Cadmium is a known environmental pollutant targeting various organs. Often implicated in cadmium toxicology is the formation of reactive oxygen species, overwhelming the free radical scavenging mechanisms and inducing ...

    • Cadmium: An Emerging Role in Adipose Tissue Dysfunction 

      Attia, Sarra Mohammed; Varadharajan, Kavitha; Shanmugakonar, Muralitharan; Das, Sandra Concepcion; Al-Naemi, Hamda A. ( Springer , 2021 , Article Review)
      Cadmium (Cd) is a toxic heavy metal that is widespread in the environment due to the substantial anthropogenic inputs from the agriculture and industrial sectors. The toxic impact of Cd adversely affects human health and ...

    • Chemokine-cytokine networks in the head and neck tumor microenvironment 

      Nisar, Sabah; Yousuf, Parvaiz; Masoodi, Tariq; Wani, Nissar A.; Hashem, Sheema; ... more authors ( MDPI , 2021 , Article Review)
      Head and neck squamous cell carcinomas (HNSCCs) are aggressive diseases with a dismal patient prognosis. Despite significant advances in treatment modalities, the five-year survival rate in patients with HNSCC has improved ...

    • Claudin-1, A Double-Edged Sword in Cancer. 

      Bhat, Ajaz A; Syed, Najeeb; Therachiyil, Lubna; Nisar, Sabah; Hashem, Sheema; ... more authors ( MDPI , 2020 , Article Review)
      Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...

    • Cytokine- and chemokine-induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy 

      Bhat, Ajaz A.; Nisar, Sabah; Singh, Mayank; Ashraf, Bazella; Masoodi, Tariq; ... more authors ( Wiley , 2022 , Article Review)
      Colorectal cancer (CRC) is a predominant life-threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment ...

    • Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy 

      Bhat, A.A.; Bhat, Ajaz A.; Nisar, Sabah; Maacha, Selma; Carneiro-Lobo, Tatiana Correa; ... more authors ( BMC , 2021 , Article Review)
      Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ...

    • Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications. 

      Sher, Gulab; Salman, Nadia Aziz; Khan, Abdul Q; Prabhu, Kirti S; Raza, Afsheen; ... more authors ( Elsevier , 2020 , Article Review)
      The global burden of breast cancer (BC) is increasing significantly. This trend is caused by several factors such as late diagnosis, limited treatment options for certain BC subtypes, drug resistance which all lead to poor ...

    • Epigenetic programing of cancer stemness by transcription factors-non-coding RNAs interactions 

      Alsayed, Reem Khaled M.E.; Sheikhan, Khalid Sultan A.M.; Alam, Majid Ali; Buddenkotte, Jorg; Steinhoff, Martin; ... more authors ( Elsevier , 2023 , Article Review)
      Cancer ‘stemness’ is fundamental to cancer existence. It defines the ability of cancer cells to indefinitely perpetuate as well as differentiate. Cancer stem cell populations within a growing tumor also help evade the ...

    • Exploring Dysregulated Signaling Pathways in Cancer. 

      Nisar, Sabah; Hashem, Sheema; Yadav, Santosh K; Muralitharan, Sankavi; Therachiyil, Lubna; ... more authors ( Bentham Science Publishers , 2020 , Article Review)
      Cancer cell biology takes advantage of identifying diverse cellular signaling pathways that are disrupted in cancer. Signaling pathways are an important means of communication from the exterior of cell to intracellular ...

    • Fc Epsilon RI–Neuroimmune Interplay in Pruritus Triggered by Particulate Matter in Atopic Dermatitis Patients 

      Isaifan, Dina; Crovella, Sergio; Soubra, Lama; Al-Nesf, Maryam; Steinhoff, Martin ( MDPI , 2023 , Article Review)
      Atopic dermatitis (AD) is the most common chronic relapsing neuroinflammatory skin disease that is characterized by a complex and multifactorial pathophysiology. It reflects a profound interplay between genetic and ...

    • Genetic and Neuroimaging Approaches to Understanding Post-Traumatic Stress Disorder. 

      Nisar, Sabah; Bhat, Ajaz A; Hashem, Sheema; Syed, Najeeb; Yadav, Santosh K; ... more authors ( MDPI , 2020 , Article Review)
      Post-traumatic stress disorder (PTSD) is a highly disabling condition, increasingly recognized as both a disorder of mental health and social burden, but also as an anxiety disorder characterized by fear, stress, and ...

    • Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder 

      Yadav, Santosh K.; Bhat, Ajaz A.; Hashem, Sheema; Nisar, Sabah; Kamal, Madeeha; ... more authors ( Springer Nature , 2021 , Article Review)
      Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental childhood-onset disorder characterized by a persistent pattern of inattentiveness, impulsiveness, restlessness, and hyperactivity. ...

    • Genetics of glutamate and its receptors in autism spectrum disorder 

      Nisar, Sabah; Bhat, Ajaz A.; Masoodi, Tariq; Hashem, Sheema; Akhtar, Sabah; ... more authors ( Springer Nature , 2022 , Article Review)
      Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by deficits in social interaction skills, impaired communication, and repetitive and restricted behaviors that are thought to be due to altered ...

    • Genetics of structural and functional brain changes in autism spectrum disorder. 

      Hashem, Sheema; Nisar, Sabah; Bhat, Ajaz A; Yadav, Santosh Kumar; Azeem, Muhammad Waqar; ... more authors ( Springer Nature , 2020 , Article Review)
      Autism spectrum disorder (ASD) is a neurological and developmental disorder characterized by social impairment and restricted interactive and communicative behaviors. It may occur as an isolated disorder or in the context ...

    • Gut Microbiota and Health: Understanding the Role of Diet 

      Alasmar, Reem Moath; Varadharajan, Kavitha; Shanmugakonar, Muralitharan; Al-Naemi, Hamda A. ( Scientific Research Publishing , 2019 , Article Review)
      Microbiome now is considered as an organ within our system to regulate metabolism, cellular immune response and eventually maintain the health. Gut microbiota has been studied extensively in the recent past due to the ...

    • Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies 

      Nisar, Sabah; Bhat, Ajaz A.; Singh, Mayank; Karedath, Thasni; Rizwan, Arshi; ... more authors ( Frontiers Media , 2021 , Article Review)
      Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be aberrant RNA splicing by-products with decreased ...

    • Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments 

      Lone, Saife N.; Nisar, Sabah; Masoodi, Tariq; Singh, Mayank; Rizwan, Arshi; ... more authors ( BMC , 2022 , Article Review)
      Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have drastically revolutionized the field of clinical ...

    • miRNAs as novel immunoregulators in cancer 

      Saife N., Lone; Bhat, Ajaz A.; Wani, Nissar A.; Karedath, Thasni; Hashem, Sheema; ... more authors ( Elsevier , 2021 , Article Review)
      The immune system is a well-known vital regulator of tumor growth, and one of the main hallmarks of cancer is evading the immune system. Immune system deregulation can lead to immune surveillance evasion, sustained cancer ...