Browsing by Author "El-Yazbi, Ahmed F."
Now showing items 1-7 of 7
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C-peptide in diabetes: A player in a dual hormone disorder?
Dakroub, Ali; Dbouk, Ali; Asfour, Aref; Nasser, Suzanne A.; El-Yazbi, Ahmed F.; Sahebkar, Amirhossein; Eid, Assaad A.; Iratni, Rabah; Eid, Ali H.... more authors ... less authors ( Wiley-Blackwell , 2024 , Article)C-peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C-peptide serves an anti-inflammatory and anti-atherogenic role in type 1 diabetes mellitus (T1DM) ... -
Dysregulation of angiotensin converting enzyme 2 expression and function in comorbid disease conditions possibly contributes to coronavirus infectious disease 2019 complication severity
Hammoud, Safaa H.; Wehbe, Zena; Abdelhady, Samar; Kobeissy, Firas; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( American Society for Pharmacology and Experimental Therapy , 2021 , Article Review)ACE2 has emerged as a double agent in the COVID-19 ordeal, as it is both physiologically protective and virally conducive. The identification of ACE2 in as many as 72 tissues suggests that extrapulmonary invasion and damage ... -
GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells
Fardoun, Manal; Nasser, Suzanne A.; El-Yazbi, Ahmed F.; Eid, Ali H. ( Wolters Kluwer Health , 2023 , Article)Raynaud's phenomenon, which results from exaggerated cold-induced vasoconstriction, is more prevalent in females than males. We previously showed that estrogen increases the expression of alpha 2C-adrenoceptors (α2C-AR), ... -
Interruption of perivascular and perirenal adipose tissue thromboinflammation rescues prediabetic cardioautonomic and renovascular deterioration
Al-Saidi, Aya; Alzaim, Ibrahim F.; Hammoud, Safaa H.; Arab, Ghida Al; Abdalla, Samaya; Mougharbil, Nahed; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( Portland Press Ltd , 2024 , Article)The cardiovascular and renovascular complications of metabolic deterioration are associated with localized adipose tissue dysfunction. We have previously demonstrated that metabolic impairment delineated the heightened ... -
Modulatory Effect of Intermittent Fasting on Adipose Tissue Inflammation: Amelioration of Cardiovascular Dysfunction in Early Metabolic Impairment
Dwaib, Haneen S.; AlZaim, Ibrahim; Eid, Ali H.; Obeid, Omar; El-Yazbi, Ahmed F. ( Frontiers , 2021 , Article)Cardiometabolic syndrome (CMS) is a cluster of maladaptive cardiovascular, renal, thrombotic, inflammatory, and metabolic disorders. It confers a high risk of cardiovascular mortality and morbidity. CMS is triggered by ... -
The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy
Bhagani, Humna; Nasser, Suzanne A.; Dakroub, Ali; El-Yazbi, Ahmed F.; Eid, Assaad A.; Kobeissy, Firas; Pintus, Gianfranco; Eid, Ali H.... more authors ... less authors ( MDPI , 2020 , Article)Diabetic cardiomyopathy (DCM) is a constellation of symptoms consisting of ventricular dysfunction and cardiomyocyte disarray in the presence of diabetes. The exact cause of this type of cardiomyopathy is still unknown; ... -
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
Dakroub, Ali; A Nasser, Suzanne; Younis, Nour; Bhagani, Humna; Al-Dhaheri, Yusra; Pintus, Gianfranco; Eid, Assaad A.; El-Yazbi, Ahmed F.; Eid, Ali H.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell colony-enhancing factor but turned out to possess enzymatic functions ...