Browsing by Author "Sourour, Idoudi"
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Role of HMGB1 and its associated signaling pathways in human malignancies
Sourour, Idoudi; Bedhiafi, Takwa; Pedersen, Shona; Elahtem, Mohamed; Alremawi, Izzaldin; Akhtar, Sabah; Dermime, Said; Merhi, Maysaloun; Uddin, Shahab... more authors ... less authors ( Elsevier , 2023 , Article)The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 ... -
Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
Sourour, Idoudi; Bedhiafi, Takwa; Sahir, Fairooz; Hijji, Yousef; Uddin, Shahab; Merhi, Maysaloun; Dermime, Said; Billa, Nashiru... more authors ... less authors ( Elsevier , 2023 , Article)Colon cancer (CRC) is the second leading cause of death and the third most diagnosed cancer worldwide. Although curcumin (CUR) has demonstrated a potent anticancer activity, it is characterized by its poor solubility, low ...