Browsing by Author "Ledgerwood, Julie E"

Now showing items 1-5 of 5

    • Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin. 

      Andrews, Sarah F; Chambers, Michael J; Schramm, Chaim A; Plyler, Jason; Raab, Julie E; ... more authors ( Elsevier , 2019 , Article)
      Vaccine-induced memory B cell responses to evolving viruses like influenza A involve activation of pre-existing immunity and generation of new responses. To define the contribution of these two types of responses, we ...

    • Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. 

      Kanekiyo, Masaru; Joyce, M Gordon; Gillespie, Rebecca A; Gallagher, John R; Andrews, Sarah F; ... more authors ( Nature Research , 2019 , Article)
      In the version of this article initially published, the labels (50 Å) above the scale bars in Fig. 1b were incorrect. The correct size is 50 nm. The error has been corrected in the HTML and PDF versions of the article.

    • Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. 

      Kanekiyo, Masaru; Joyce, M Gordon; Gillespie, Rebecca A; Gallagher, John R; Andrews, Sarah F; ... more authors ( Nature Research , 2019 , Article)
      The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy. This necessitates new approaches that provide ...

    • Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera. 

      Yassine, Hadi M; McTamney, Patrick M; Boyington, Jeffery C; Ruckwardt, Tracy J; Crank, Michelle C; ... more authors ( Nature Publishing Group , 2018 , Article)
      A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, ...

    • Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses 

      Joyce, M. Gordon; Wheatley, Adam K.; Thomas, Paul V.; Chuang, Gwo-Yu; Soto, Cinque; ... more authors ( Elsevier Inc. , 2016 , Article)
      Antibodies capable of neutralizing divergent influenza A viruses could form the basis of a universal vaccine. Here, from subjects enrolled in an H5N1 DNA/MIV-prime-boost influenza vaccine trial, we sorted hemagglutinin ...