Browsing by Author "Ramchandran, Ramani"

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Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish (Danio rerio)

Eisa-Beygi, Shahram; Benslimane, Fatiha M.; El-Rass, Suzan; Prabhudesai, Shubhangi; Abdelrasoul, Mahmoud Khatib Ali; Simpson, Pippa M.; yalcin, Huseyin C.; Burrows, Patricia E.; Ramchandran, Ramani... more authors ... less authors ( American Heart Association , 2018 , Article)
Objective—Endothelial cells (ECs) sense and respond to flow-induced mechanical stress, in part, via microtubule-based projections called primary cilia. However, many critical steps during vascular morphogenesis occur ...
Cilia proteins are biomarkers of altered flow in the vasculature

Gupta, Ankan; Thirugnanam, Karthikeyan; Thamilarasan, Madhan; Mohieldin, Ashraf M.; Zedan, Hadeel T.; Prabhudesai, Shubhangi; Griffin, Meghan R.; Spearman, Andrew D.; Pan, Amy; Palecek, Sean P.; Yalcin, Huseyin C.; Nauli, Surya M.; Rarick, Kevin R.; Zennadi, Rahima; Ramchandran, Ramani... more authors ... less authors ( American Society for Clinical Investigation , 2022 , Article)
Cilia, microtubule-based organelles that project from the apical luminal surface of endothelial cells (ECs), are widely regarded as low-flow sensors. Previous reports suggest that upon high shear stress, cilia on the EC ...