Browsing by Author "Bitto, Alessandra"
Now showing items 1-5 of 5
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Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells
Mannino, Federica; Pallio, Giovanni; Corsaro, Roberta; Minutoli, Letteria; Altavilla, Domenica; Vermiglio, Giovanna; Allegra, Alessandro; Eid, Ali H.; Bitto, Alessandra; Squadrito, Francesco; Irrera, Natasha... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Cannabinoid receptors, which are widely distributed in the body, have been considered as possible pharmacological targets for the management of several tumors. Cannabinoid type 2 receptors (CB2Rs) belong to the G protein-coupled ... -
Could antigen presenting cells represent a protective element during sars-cov-2 infection in children?
Lauro, Rita; Irrera, Natasha; Eid, Ali H.; Bitto, Alessandra ( MDPI , 2021 , Article)Antigen Presenting Cells (APC) are immune cells that recognize, process, and present antigens to lymphocytes. APCs are among the earliest immune responders against an antigen. Thus, in patients with COVID-19, a disease ... -
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
Fardoun, Manal Muin; Maaliki, Dina; Halabi, Nabil; Iratni, Rabah; Bitto, Alessandra; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Portland Press Ltd , 2020 , Article Review)Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ... -
Mechanisms underlying the effects of caloric restriction on hypertension
Ahmad A., Al Attar; Fahed, Gracia I.; Hoballah, Malak M.; Pedersen, Shona; El-Yazbi, Ahmed F.; Nasser, Suzanne A.; Bitto, Alessandra; Orekhov, Alexander N.; Eid, Ali H.... more authors ... less authors ( Elsevier , 2022 , Article)Hypertension is a major risk factor for cardiovascular disease (CVD) as well as a major contributor to all-cause mortality and disability worldwide. The pathophysiology of hypertension is highly attributed to a dysfunctional ... -
Recent advances in nanotherapeutics for multiple myeloma
Iannazzo, Daniela; Ettari, Roberta; Giofrè, Salvatore; Eid, Ali H.; Bitto, Alessandra ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Anticancer therapies cannot be included in a one-size-fits-all scenario; it is imperative to adapt therapies to the tumor molecular profile and most importantly to develop target-specific therapeutics. Nanotherapeutics can ...