Browsing by Author "Smatti, Maria K."

Now showing items 1-20 of 47

    • Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis 

      Thomas, Swapna; Smatti, Maria K.; Ouhtit, Allal; Cyprian, Farhan S.; Almaslamani, Muna A.; ... more authors ( Elsevier Ltd , 2022 , Article Review)
      Antibody-dependent enhancement (ADE) has been associated with severe disease outcomes in several viral infections, including respiratory infections. In vitro and in vivo studies showed that antibody-response to SARS-CoV ...

    • Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination 

      Zedan, Hadeel T.; Smatti, Maria K.; Thomas, Swapna; Nasrallah, Gheyath K.; Afifi, Nahla M.; ... more authors ( American Medical Association , 2023 , Article)
      Importance: In the ongoing COVID-19 pandemic, there remain unanswered questions regarding the nature and importance of the humoral immune response against other coronaviruses. Although coinfection of the Middle East ...

    • CO-PREVALENCE OF HUMAN PAPILLOMAVIRUS AND EPSTEIN BARR VIRUS IN HEALTHY BLOOD DONORS IN QATAR 

      Gupta, Ishita; Jabeen, Ayesha; Smatti, Maria K.; Al-Thawadi, Hamda A.; Nasrallah, Gheyath K.; ... more authors ( Qatar University Press , 2020 , Poster)
      Introduction: Infections with human oncoviruses such as high-risk human papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are globally prevalent in the adult population. Both viruses are strongly associated with several ...

    • Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants 

      Hebah A., Al-Khatib; Smatti, Maria K.; Ali, Fatma H.; Zedan, Hadeel T.; Thomas, Swapna; ... more authors ( Elsevier , 2022 , Article)
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ...

    • Coronavirus Disease 2019 Disease Severity in Children Infected With the Omicron Variant 

      Butt, A.A.; Butt, Adeel A.; Dargham, Soha R.; Loka, Srusvin; Shaik, Riyazuddin M.; ... more authors ( NLM (Medline) , 2022 , Article)
      SHORT SUMMARY: Severe acute respiratory syndrome coronavirus 2 infection from the Omicron variant in children/adolescents is less severe than infection from the Delta variant. Those 6 to <18 years also have less severe ...

    • Correction to: Co-prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar 

      Gupta, Ishita; Nasrallah, Gheyath K.; Sharma, Anju; Jabeen, Ayesha; Smatti, Maria K.; ... more authors ( BMC , 2020 , Other)
      Correction to: Cancer Cell Int (2020) 20:107 https://doi.org/10.1186/s12935-020-01190-2

    • Covid-19 Vaccine Protection among Children and Adolescents in Qatar. 

      Chemaitelly, Hiam; AlMukdad, Sawsan; Ayoub, Houssein H; Altarawneh, Heba N; Coyle, Peter; ... more authors ( Massachusetts Medical Society , 2022 , Article)
      The BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) has been authorized for use in children 5 to 11 years of age and adolescents 12 to 17 years of age but in different antigen doses. We assessed the real-world ...

    • Demographics and Epidemiology of Hepatitis B in the State of Qatar: A Five-Year Surveillance-Based Incidence Study 

      Al Romaihi, Hamad E.; Ganesan, Nandakumar; Farag, Elmoubasher A.; Smatti, Maria K.; Nasrallah, Gheyath K.; ... more authors ( MDPI , 2019 , Article)
      Background: Expatriates represent >80% of Qatar’s population, mostly arriving from countries in Africa and Asia that are endemic with many diseases. This increases the risk for introducing new pathogens into the country ...

    • Distinct antibody repertoires against endemic human coronaviruses in children and adults. 

      Khan, Taushif; Rahman, Mahbuba; Al Ali, Fatima; Huang, Susie Sy; Ata, Manar; ... more authors ( American Society for Clinical Investigation , 2021 , Article)
      Four endemic human coronaviruses (HCoVs) are commonly associated with acute respiratory infection in humans. B cell responses to these "common cold" viruses remain incompletely understood. Here we report a comprehensive ...

    • Diversity of bacterial pathogens and their antimicrobial resistance profile among commensal rodents in Qatar 

      Islam, M.M.; Islam, Md Mazharul; Farag, Elmoubashar; Hassan, Mohammad Mahmudul; Enan, Khalid A.; ... more authors ( Springer Science and Business Media B.V. , 2022 , Article)
      Rodents are sources of many zoonotic pathogens that are of public health concern. This study investigated bacterial pathogens and assessed their antimicrobial resistance (AMR) patterns in commensal rodents in Qatar. A total ...

    • Duration of immune protection of SARS-CoV-2 natural infection against reinfection. 

      Chemaitelly, Hiam; Nagelkerke, Nico; Ayoub, Houssein H; Coyle, Peter; Tang, Patrick; ... more authors ( Oxford University Press , 2022 , Article)
      The future of the SARS-CoV-2 pandemic hinges on virus evolution and duration of immune protection of natural infection against reinfection. We investigated duration of protection afforded by natural infection, the effect ...

    • Duration of mRNA vaccine protection against SARS-CoV-2 Omicron BA.1 and BA.2 subvariants in Qatar. 

      Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Coyle, Peter; Tang, Patrick; ... more authors ( Nature Research , 2022 , Article)
      SARS-CoV-2 Omicron BA.1 and BA.2 subvariants are genetically divergent. We conducted a matched, test-negative, case-control study to estimate duration of protection of the second and third/booster doses of mRNA COVID-19 ...

    • Effect of mRNA Vaccine Boosters against SARS-CoV-2 Omicron Infection in Qatar. 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Yassine, Hadi M; ... more authors ( Massachusetts Medical Society , 2022 , Article)
      Waning of vaccine protection against coronavirus disease 2019 (Covid-19) and the emergence of the omicron (or B.1.1.529) variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have led to expedited ...

    • Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections. 

      Qassim, Suelen H; Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Tang, Patrick; ... more authors ( Oxford University Press , 2022 , Article)
      Compared to BA.1, BA.2 was associated with lower RT-qPCR cycle threshold (Ct) value-3.53 fewer cycles (95% CI: 3.46-3.60), signifying higher infectiousness. This may reflect higher viral load and/or longer duration of ...

    • Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections. 

      Altarawneh, Heba N; Chemaitelly, Hiam; Ayoub, Houssein H; Tang, Patrick; Hasan, Mohammad R; ... more authors ( Massachusetts Medical Society , 2022 , Article)
      The protection conferred by natural immunity, vaccination, and both against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with the BA.1 or BA.2 sublineages of the omicron (B.1.1.529) ...

    • Effects of SARS-CoV-2 Alpha, Beta, and Delta variants, age, vaccination, and prior infection on infectiousness of SARS-CoV-2 infections 

      Qassim, Suelen H.; Hasan, Mohammad R.; Tang, Patrick; Chemaitelly, Hiam; Ayoub, Houssein H.; ... more authors ( Frontiers Media , 2022 , Article)
      In 2021, Qatar experienced considerable incidence of SARS-CoV-2 infection that was dominated sequentially by the Alpha, Beta, and Delta variants. Using the cycle threshold (Ct) value of an RT-qPCR-positive test to proxy ...

    • Epidemiological, Molecular, and Clinical Features of Norovirus Infections among Pediatric Patients in Qatar 

      Mathew, Shilu; Alansari, Khalid; Smatti, Maria K.; Zaraket, Hassan; Al Thani, Asmaa A.; ... more authors ( MDPI , 2019 , Article)
      Abstract: Background: Norovirus (NoV) is recognized as the second most important etiological agent leading to acute gastroenteritis globally. In order to determine the burden and characteristics of NoV infections in children ...

    • Epidemiology of respiratory infections among adults in Qatar (2012-2017). 

      Al-Romaihi, Hamad Eid; Smatti, Maria K; Ganesan, Nandakumar; Nadeem, Shazia; Farag, Elmoubasher; ... more authors ( Public Library of Science , 2019 , Article)
      Limited data is available about the etiology of influenza like illnesses (ILIs) in Qatar. This study aimed at providing preliminary estimates of influenza and other respiratory infections circulating among adults in Qatar. ...

    • Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update 

      Smatti, Maria K.; Al-Sadeq, Duaa W.; Ali, Nadima H.; Pintus, Gianfranco; Abou-Saleh, Haissam; ... more authors ( Frontiers Medi , 2018 , Article Review)
      The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent of infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to ...

    • Hepatitis B Virus Molecular Epidemiology, Host-Virus Interaction, Coinfection, and Laboratory Diagnosis in the MENA Region: An Update 

      Al-Sadeq, Duaa W.; Taleb, Sara A.; Zaied, Roan E.; Fahad, Sara M.; Smatti, Maria K.; ... more authors ( MDPI , 2019 , Article)
      Hepatitis B virus (HBV) is an enveloped partial double-stranded DNA virus that can cause acute and chronic hepatitis. According to the World Health Organization (WHO) and the Centers for Disease Control and Prevention ...