Browsing by Author "Joseph, Jensa"
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Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer
Gorachinov, Filip; Mraiche, Fatima; Moustafa, Diala Alhaj; Hishari, Ola; Ismail, Yomna; Joseph, Jensa; Crcarevska, Maja Simonoska; Dodov, Marija Glavas; Geskovski, Nikola; Goracinova, Katerina... more authors ... less authors ( Beilstein-Institut Zur Forderung der Chemischen Wissenschaften , 2023 , Article)Genomic and proteomic mutation analysis is the standard of care for selecting candidates for therapies with tyrosine kinase inhibitors against the human epidermal growth factor receptor (EGFR TKI therapies) and further ... -
The Cardiovascular Benefits of Empagliflozin, A Sodium Glucose Cotransporter Inhibitor: Is NHE1 a Viable Target?
Al-Shamasi, Al-Anood; Elsayed, Meram; Abdulrahman, Nabeel; Joseph, Jensa; Mraiche, Fatima ( Qatar University Press , 2020 , Poster)Empagliflozin (EMPA), an SGLT2 inhibitor (with a low affinity for SGLT1) has attracted much attention due to a recent clinical trial, the Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes (EMPA-REG ... -
The Cellular Interplay Between CD44 and Na+/H+ Exchanger1 in Cardiac Remodeling
Mraiche, Fatima; Suleiman, Muna; Abdulrahman, Nabeel; Joseph, Jensa ( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Background: Extracellular matrix (ECM) remodeling is a characteristic feature of cardiac remodeling which, if left untreated, progresses to heart failure. Cardiac fibroblasts, the major cellular component of the myocardium, ...