Browsing by Author "Allouch, Soumaya"
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AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
Allouch, Soumaya; Munusamy, Shankar ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Background: Chronic kidney disease (CKD) is characterized by progressive decline in renal function; if left untreated, it ultimately results in end-stage renal disease (ESRD), a condition that demands either dialysis or ... -
Between Inflammation and Autophagy: The Role of Leptin-Adiponectin Axis in Cardiac Remodeling
Kamareddine, Layla; Ghantous, Crystal; Allouch, Soumaya; Al-Ashmar, Sara; Anlar, Gulsen; Kannan, Surya; Djouhri, Laiche; Korashy, Hesham; Agouni, Abdelali; Zeidan, Asad... more authors ... less authors ( Dove Medical Press , 2021 , Article Review)Cardiac remodeling is the process by which the heart adapts to stressful stimuli, such as hypertension and ischemia/reperfusion; it ultimately leads to heart failure upon long- term exposure. Autophagy, a cellular catabolic ... -
Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype.
Allouch, Soumaya; Gupta, Ishita; Malik, Shaza; Al Farsi, Halema F; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( Frontiers Media , 2020 , Article)Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular, gestational breast cancer is considered one of the most aggressive types of cancers, which is a rare but fatal disease. However, the ... -
High-Risk HPV Oncoproteins and PD-1/PD-L1 Interplay in Human Cervical Cancer: Recent Evidence and Future Directions
Allouch, Soumaya; Malki, Ahmed; Allouch, Asma; Gupta, Ishita; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( Frontiers Media , 2020 , Article)Cervical cancer is the fourth most common malignancy in women worldwide and a leading cause of cancer-related mortality in developing countries. Important etiological factors in this cancer are high-risk human papillomaviruses ... -
Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.
Fernandes, Queenie; Allouch, Soumaya; Gupta, Ishita; Elmakaty, Ibrahim; Elzawawi, Khaled E; Amarah, Ahmed; Al-Thawadi, Hamda; Al-Farsi, Halema; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( MDPI , 2022 , Article Review)The human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered ... -
Metformin Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
Allouch, Soumaya; Munusamy, Shankar ( Wiley Periodicals, Inc , 2017 , Article)Proteinuria (albuminuria) plays a crucial role in the etiology of chronic kidney disease (CKD) via alteration of multiple signaling pathways and cellular process in renal cells. The objectives of this study are to investigate ... -
PROTECTIVE EFFECTS OF METFORMIN IN AN IN VITRO MODEL OF PROTEINURIC KIDNEY DISEASE
Allouch, Soumaya (2017 , Master Thesis)Albuminuria, a hallmark of chronic kidney disease (CKD), plays a crucial role in the etiology of CKD. High albumin levels are thought to induce endoplasmic reticulum (ER) stress and activate the AKT pathway, and lead to ...