Browsing by Author "Senarathne, Wijendra"
Now showing items 1-4 of 4
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Biomarkers of Targeted Therapy and Immuno-Oncology in Cancers Metastatic to the Breast.
Vranic, Semir; Senarathne, Wijendra; Stafford, Phillip; Poorman, Kelsey; Pockaj, Barbara A; Gatalica, Zoran... more authors ... less authors ( Lippincott, Williams & Wilkins , 2019 , Article)The breast is a rare site for metastases, and their molecular characteristics have not been studied yet. Intrinsic molecular genetics, cancer characteristics, and breast tissue immune responses in diverse metastases to the ... -
Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget's disease.
Gatalica, Zoran; Vranic, Semir; Krušlin, Božo; Poorman, Kelsey; Stafford, Phillip; Kacerovska, Denisa; Senarathne, Wijendra; Florento, Elena; Contreras, Elma; Leary, Alexandra; Choi, April; In, Gino K... more authors ... less authors ( Wiley Open Access , 2020 , Article)Primary Extra-mammary Paget's disease (EMPD) is a very rare cutaneous adenocarcinoma affecting anogenital or axillary regions. It is characterized by a prolonged course with recurrences and eventually distant metastatic ... -
Composition of the immune microenvironment differs between carcinomas metastatic to the lungs and primary lung carcinomas.
Senarathne, Wijendra; Vranic, Semir; Xiu, Joanne; Rose, Inga; Gates, Peggy; Gatalica, Zoran... more authors ... less authors ( Elsevier , 2018 , Article)Lungs are among the most common sites for development of both primary and metastatic carcinomas. Tumor cells expression (TC) of PD-L1 is an important predictor of the of response to immune check-point inhibition in NSCLC, ... -
Novel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profiling.
Gargano, Stacey M; Senarathne, Wijendra; Feldman, Rebecca; Florento, Elena; Stafford, Phillip; Swensen, Jeffrey; Vranic, Semir; Gatalica, Zoran... more authors ... less authors ( Wiley Open Access , 2019 , Article)Salivary duct carcinoma (SDC) is a rare, aggressive salivary gland malignancy, which often presents at an advanced stage. A proportion of SDC are characterized by HER2 amplification and/or overexpression of androgen receptor ...