Browsing by Author "Webster, Thomas J."
Now showing items 1-8 of 8
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CTGF Loaded Electrospun Dual Porous Core-Shell Membrane For Diabetic Wound Healing
Augustine, Robin; Zahid, Alap Ali; Hasan, Anwarul; Wang, Mian; Webster, Thomas J ( Dove Medical Press Ltd. , 2019 , Article)Purpose: Impairment of wound healing is a major issue in type-2 diabetes that often causes chronic infections, eventually leading to limb and/or organ amputation. Connective tissue growth factor (CTGF) is a signaling ... -
Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles
Al-Fahdawi, Mohamed Qasim; Rasedee, Abdullah; Al-Qubaisi, Mothanna Sadiq; Alhassan, Fatah H.; Rosli, Rozita; El Zowalaty, Mohamed Ezzat; Naadja, Seif-Eddine; Webster, Thomas J.; Taufiq-Yap, Yun Hin... more authors ... less authors ( Dove Press , 2015 , Article)Iron–manganese-doped sulfated zirconia nanoparticles with both Lewis and Brønsted acidic sites were prepared by a hydrothermal impregnation method followed by calcination at 650°C for 5 hours, and their cytotoxicity ... -
Growth factor releasing core-shell polymeric scaffolds for tissue engineering applications
Augustine, Robin; Zahid, Alap; Wang, Mian; Webster, Thomas j.; Hasan, Anwarul ( Institute of Electrical and Electronics Engineers Inc. , 2019 , Conference Paper)Tissue engineering is the use of a combination of cells, biomaterials and appropriate signals to repair or improve the functions of damaged tissues. Our group is exploiting various approaches to effectively encapsulate ... -
Paclitaxel/methotrexate co-loaded PLGA nanoparticles in glioblastoma treatment: Formulation development and in vitro antitumor activity evaluation
Fatemeh, Madani; Esnaashari, Seyedeh Sara; Bergonzi, Maria Camilla; Webster, Thomas J.; Younes, Husam M.; Khosravani, Masood; Adabi, Mahdi... more authors ... less authors ( Elsevier , 2020 , Article)AimThe aim of this study was to improve the therapeutic index of chemotherapeutic drugs on glioblastoma cells through an improved co-drug delivery system. Materials and methodsMethotrexate (MTX) and paclitaxel (PTX) were ... -
Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease
Firouzamandi, Masoumeh; Moeini, Hassan; Hosseini, Seyed Davood; Bejo, Mohd Hair; Omar, Abdul Rahman; Mehrbod, Parvaneh; El Zowalaty, Mohamed E.; Webster, Thomas J.; Ideris, Aini... more authors ... less authors ( Dove Press , 2016 , Article)Plasmid DNA (pDNA)-based vaccines have emerged as effective subunit vaccines against viral and bacterial pathogens. In this study, a DNA vaccine, namely plasmid internal ribosome entry site-HN/F, was applied in ovo against ... -
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
El Zowalaty, Mohamed E.; Al Thani, Asmaa A.; Webster, Thomas J.; El Zowalaty, Ahmed E.; Schweizer, Herbert P.; Nasrallah, Gheyath K.; Marei, Hany E.; Ashour, Hossam M.... more authors ... less authors ( Future Medicine , 2015 , Article)Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ... -
Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing
Hassiba, Alaa J.; El Zowalaty, Mohamed E.; Nasrallah, Gheyath K.; Webster, Thomas J.; Luyt, Adriaan S.; Abdullah, Aboubakr M.; Elzatahry, Ahmed A.... more authors ... less authors ( Future Medicine , 2016 , Article)Wound dressings play an important role in a patient’s recovery from health problems, as unattended wounds could lead to serious complications such as infections or, ultimately, even death. Therefore, wound dressings since ... -
Synthesis, characterization, and antimicrobial properties of novel double layer nanocomposite electrospun fibers for wound dressing applications
Hassiba, Alaa J.; El Zowalaty, Mohamed E.; Webster, Thomas J.; Abdullah, Aboubakr M.; Nasrallah, Gheyath K.; Khalil, Khalil Abdelrazek; Luyt, Adriaan S.; Elzatahry, Ahmed A.... more authors ... less authors ( Dove Press , 2017 , Article)Herein, novel hybrid nanomaterials were developed for wound dressing applications with antimicrobial properties. Electrospinning was used to fabricate a double layer nanocomposite nanofibrous mat consisting of an upper ...