Browsing by Author "Eid A."
Now showing items 1-4 of 4
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7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells
Fardoun M.; Iratni R.; Dehaini H.; Eid A.; Ghaddar T.; El-Elimat T.; Alali F.; Badran A.; Eid A.H.; Baydoun E.... more authors ... less authors ( MDPI AG , 2019 , Article)Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ... -
Carnosol induces ROS-mediated beclin1-independent autophagy and apoptosis in triple negative breast cancer
Al Dhaheri, Y.; Attoub, S.; Ramadan, G.; Arafat, K.; Bajbouj, K.; Karuvantevida, N.; AbuQamar, S.; Eid, A.; Iratni, R.... more authors ... less authors ( Public Library of Science , 2014 , Article)Background: In this study we investigated the in vitro and in vivo anticancer effect of carnosol, a naturally occurring polyphenol, in triple negative breast cancer.Results: We found that carnosol significantly inhibited ... -
Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
Ouhtit A.; Gupta I.; Gaur R.L.; Fernando A.; Abd El-Azim A.O.; Eid A.; Becker T.M.... more authors ... less authors ( Frontiers in Bioscience , 2020 , Article Review)We have previously characterized the role of p16/Rb in coordinating the early events in UVB-irradiated skin. As an extension to this work, normal melanocytes and mutant p16-inducible melanoma cell models were employed to ... -
Direct cardiovascular impact of SGLT2 inhibitors: mechanisms and effects
Kaplan A.; Abidi E.; El-Yazbi A.; Eid A.; Booz G.W.; Zouein F.A.... more authors ... less authors ( Springer New York LLC , 2018 , Article Review)Diabetes is a global epidemic and a leading cause of death with more than 422 million patients worldwide out of whom around 392 million alone suffer from type 2 diabetes (T2D). Sodium-glucose cotransporter 2 inhibitors ...