Browsing by Author "nr 98036333"
Now showing items 1-4 of 4
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A population study of clinically actionable genetic variation affecting drug response from the Middle East
Jithesh, Puthen Veettil; Abuhaliqa, Mohammed; Syed, Najeeb; Ahmed, Ikhlak; El Anbari, Mohammed; Bastaki, Kholoud; Sherif, Shimaa; Umlai, Umm-Kulthum; Jan, Zainab; Gandhi, Geethanjali; Manickam, Chidambaram; Selvaraj, Senthil; George, Chinnu; Bangarusamy, Dhinoth; Abdel-latif, Rania; Al-Shafai, Mashael; Tatari-Calderone, Zohreh; Estivill, Xavier; Pirmohamed, Munir; Abdel-latif, Rania; Saqri, Tariq Abu; Zaid, Tariq Abu; Afifi, Nahla; Al-Ali, Rashid; Al-Khodor, Souhaila; Al-Muftah, Wadha; Al-Sarraj, Yasser; Albagha, Omar; Alkhayat, Eiman; Alkuwari, Fatima; Almabrazi, Hakeem; Alshafai, Mashael; Althani, Asmaa; Alvi, Muhammad; Badii, Ramin; Badji, Radja; Chouchane, Lotfi; Darwish, Dima; El Khouly, Ahmed; Ennaifar, Maryem; Estivill, Xavier; Fadl, Tasnim; Fakhro, Khalid; Fethnou, Eleni; Hamza, Mehshad; Ismail, Said I.; Jithesh, Puthen V.; Khatib, Mohammedhusen; Liu, Wei; Lorenz, Stephan; Mbarek, Hamdi; Mokrab, Younes; Pathare, Tushar; Poolat, Shafeeq; Qafoud, Fatima; Vempalli, Fazulur Rehaman; Saad, Chadi; Suhre, Karsten; Syed, Najeeb; Tatari, Zohreh; Temanni, Ramzi; Tomei, Sara; Yasin, Heba... more authors ... less authors ( Nature Research , 2022 , Article)Clinical implementation of pharmacogenomics will help in personalizing drug prescriptions and alleviate the personal and financial burden due to inefficacy and adverse reactions to drugs. However, such implementation is ... -
High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines
Rinchai, Darawan; Deola, Sara; Zoppoli, Gabriele; Kabeer, Basirudeen Syed Ahamed; Taleb, Sara; Pavlovski, Igor; Maacha, Selma; Gentilcore, Giusy; Toufiq, Mohammed; Mathew, Lisa; Liu, Li; Vempalli, Fazulur Rehaman; Mubarak, Ghada; Lorenz, Stephan; Sivieri, Irene; Cirmena, Gabriella; Dentone, Chiara; Cuccarolo, Paola; Giacobbe, Daniele Roberto; Baldi, Federico; Garbarino, Alberto; Cigolini, Benedetta; Cremonesi, Paolo; Bedognetti, Michele; Ballestrero, Alberto; Bassetti, Matteo; Hejblum, Boris P.; Augustine, Tracy; Van Panhuys, Nicholas; Thiebaut, Rodolphe; Branco, Ricardo; Chew, Tracey; Shojaei, Maryam; Short, Kirsty; Feng, Carl G.; Zughaier, Susu M.; De Maria, Andrea; Tang, Benjamin; Hssain, Ali Ait; Bedognetti, Davide; Grivel, Jean Charles; Chaussabel, Damien... more authors ... less authors ( American Association for the Advancement of Science , 2022 , Article)Knowledge of the mechanisms underpinning the development of protective immunity conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus disease 2019 (COVID-19) mRNA vaccination via ... -
Real-Time SARS-CoV-2 Genotyping by High-Throughput Multiplex PCR Reveals the Epidemiology of the Variants of Concern in Qatar
R. Hasan, Mohammad; K.R. Kalikiri, Mahesh; Mirza, Faheem; Sundararaju, Sathyavathi; Sharma, Anju; Xaba, Thabisile; Lorenz, Stephan; Chemaitelly, Hiam; A. El-Kahlout, Reham; Ming Tsui, Kin; M. Yassine, Hadi; V. Coyle, Peter; Al Khal, Abdullatif; Bertollini, Roberto; H. Al Thani, Mohamed; J. Abu-Raddad, Laith; Tang, Patrick... more authors ... less authors ( Elsevier , 2021 , Article)Complementing whole genome sequencing strategies with high-throughput multiplex RT-qPCR genotyping allows for more comprehensive and real-time tracking of SARS-CoV-2 variants of concern. During the second and third waves ... -
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
Da’as, Sahar Isa; Hasan, Waseem; Salem, Rola; Younes, Nadine; Abdelrahman, Doua; Mohamed, Iman A.; Aldaalis, Arwa; Temanni, Ramzi; Mathew, Lisa Sara; Lorenz, Stephan; Yacoub, Magdi; Nomikos, Michail; Nasrallah, Gheyath K.; Fakhro, Khalid A.... more authors ... less authors ( MDPI , 2022 , Article)Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate ...