HER-2/Epstein-Barr virus crosstalk in human gastric carcinogenesis: A novel concept of oncogene/oncovirus interaction.
| Author | Cyprian, Farhan S |
| Author | Al-Antary, Noor |
| Author | Al Moustafa, Ala-Eddin |
| Available date | 2019-10-16T06:55:13Z |
| Publication Date | 2018-01-02 |
| Publication Name | Cell Adhesion and Migration |
| Identifier | http://dx.doi.org/10.1080/19336918.2017.1330244 |
| Citation | Ruizhen Liu, Yi Kong, Pengbo Sun, Faliang Li, Xiaopeng Shi. (2019) Correlation between methylation of the caveolin‐1 gene and of caveolin‐1 messenger ribonucleic acid, and protein levels and human epidermal growth factor receptor 2 protein expression in adenocarcinomas of the esophagogastric junction. Precision Radiation Oncology 3:1, pages 8-14. |
| ISSN | 1933-6918 |
| Abstract | Gastric cancer is the fourth most common cancer and the second leading cause of cancer deaths worldwide. Additionally, it is well-known that metastatic cancer disease is a major cause of morbidity and mortality in cancer patients. Several investigations reported that HER-2 (ErbB-2 receptor) and Epstein-Barr virus (EBV) are important etiological factors in human gastric cancer, where either oncogene/oncovirus alone can derive a major event of cancer progression and metastasis via epithelial-mesenchymal transition (EMT). Herein, we discuss, for the first time, the possibility of HER-2/EBV-oncoproteins interaction in human gastric cancer initiation and/or progression. |
| Sponsor | Our research is supported by the College of Medicine and Qatar University. |
| Language | en |
| Publisher | Taylor & Francis |
| Subject | EBV HER-2 cancer initiation and progression gastric cancer oncogene/oncovirus cooperation |
| Type | Article |
| Pagination | 1-4 |
| Issue Number | 1 |
| Volume Number | 12 |
| ESSN | 1933-6926 |
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