تصفح Academic حسب المؤلف "Ardah, Mustafa T."
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Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils
Ardah, Mustafa T.; Paleologou, Katerina E.; Lv, Guohua; Menon, Sindhu A.; Abul Khair, Salema B.; Lu, Jia-Hong; Safieh-Garabedian, Bared; Al-Hayani, Abdulmonem A.; Eliezer, David; Li, Min; El-Agnaf, Omar M.A.... more authors ... less authors ( Elsevier , 2015 , Article)Compelling evidence indicates that α-synuclein (α-syn) aggregation plays a central role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies. Identification of compounds that inhibit or reverse the ... -
Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease
Majbour, Nour K.; Vaikath, Nishant N.; van Dijk, Karin D.; Ardah, Mustafa T.; Varghese, Shiji; Vesterager, Louise B.; Montezinho, Liliana P.; Poole, Stephen; Safieh-Garabedian, Bared; Tokuda, Takahiko; Teunissen, Charlotte E.; Berendse, Henk W.; van de Berg, Wilma D. J.; El-Agnaf, Omar M. A.... more authors ... less authors ( BioMed Central , 2016 , Article)Background Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson’s disease (PD) based on biochemical analysis of blood or CSF. However, neurodegeneration in the brains of PD patients ...