Browsing Medicine Research by Author "Sadek, Bassem"
Now showing items 1-2 of 2
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Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
Sadek, Bassem; Oz, Murat; Nurulain, Syed M.; Jayaprakash, Petrilla; Latacz, Gniewomir; Kieć-Kononowicz, Katarzyna; Szymańska, Ewa... more authors ... less authors ( Elsevier B.V. , 2017 , Article)The critical role of α1-glycine receptor (α1-GLYRs) in pathological conditions such as epilepsy is well known. In the present study, structure-activity relations for a series of phenylalanine derivatives carrying selected ... -
Thujone inhibits the function of 7-nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm
Sultan, Ahmed; Yang, Keun-Hang Susan; Isaev, Dmitro; ElNebrisi, Eslam; Syed, Nurulain; Khan, Nadia; Howarth, Christopher F.; Sadek, Bassem; Ozad, Murat... more authors ... less authors ( Elsevier Ireland Ltd , 2017 , Article)Effects of thujone, a major ingredient of absinthe, wormwood oil and some herbal medicines, were tested on the function of 7 subunit of the human nicotinic acetylcholine (7 nACh) receptor expressed in Xenopus oocytes using ...