Browsing Medicine Research by Author "Abou-Samra, Abdul Badi"
Now showing items 1-10 of 10
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Characteristic MicroRNAs Linked to Dysregulated Metabolic Pathways in Qatari Adult Subjects With Obesity and Metabolic Syndrome.
Mir, Fayaz Ahmad; Mall, Raghvendra; Iskandarani, Ahmad; Ullah, Ehsan; Samra, Tareq A; Cyprian, Farhan; Parray, Aijaz; Alkasem, Meis; Abdalhakam, Ibrahem; Farooq, Faisal; Abou-Samra, Abdul-Badi... more authors ... less authors ( Frontiers , 2022 , Article)Obesity-associated dysglycemia is associated with metabolic disorders. MicroRNAs (miRNAs) are known regulators of metabolic homeostasis. We aimed to assess the relationship of circulating miRNAs with clinical features in ... -
A Delphi consensus study introducing a Problem And attRibutes‐bAsed DIabetes self‐manaGeMent (PARADIGM) intervention for patients with type 2 diabetes
Manal M., Othman; Khudadad, Hanan; Dughmosh, Ragae; Kane, Tanya; Abou-Samra, Abdul-Badi; Doi, Suhail A.R.... more authors ... less authors ( Elsevier , 2022 , Article)AimEncouraging patients to improve their self-management behavior based on a strict definition of the intervention is important for a standardized delivery but, until recently, there was no consensus on the core attributes ... -
Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome
Mir, Fayaz Ahmad; Ullah, Ehsan; Mall, Raghvendra; Iskandarani, Ahmad; Samra, Tareq A.; Cyprian, Farhan; Parray, Aijaz; Alkasem, Meis; Abdalhakam, Ibrahem; Farooq, Faisal; Abou-Samra, Abdul Badi... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: Obesity coexists with variable features of metabolic syndrome, which is associated with dysregulated metabolic pathways. We assessed potential associations between serum metabolites and features of metabolic ... -
The impact of prior obesity surgery on glucose metabolism after body contouring surgery: A pilot study.
Badran, Saif; Doi, Suhail A; Hammouda, Atalla; Khoogaly, Hoda; Muneer, Mohammad; Alkasem, Meis J; Abou-Samra, Abdul-Badi; Habib, Abdella M... more authors ... less authors ( Europe PMC , 2023 , Article)Body contouring surgery enhances physical appearance by means of surgical subcutaneous fat removal (SSFR). However, it remains unclear how SSFR may affect glucose metabolism and its broader effects on the endocrine system, ... -
Inflammatory protein signatures in individuals with obesity and metabolic syndrome
Mir, Fayaz Ahmad; Abdesselem, Houari B.; Cyprian, Farhan; Iskandarani, Ahmad; Doudin, Asmma; Samra, Tareq A.; Alkasem, Meis; Abdalhakam, Ibrahem; Taheri, Shahrad; Abou-Samra, Abdul Badi... more authors ... less authors ( Springer Nature , 2023 , Article)There is variability in the metabolic health status among individuals presenting with obesity; some may be metabolically healthy, while others may have developed the metabolic syndrome, a cluster including insulin resistance, ... -
An integrated multi-omic approach demonstrates distinct molecular signatures between human obesity with and without metabolic complications: a case–control study
Mir, Fayaz Ahmad; Mall, Raghvendra; Ullah, Ehsan; Iskandarani, Ahmad; Cyprian, Farhan; Samra, Tareq A.; Alkasem, Meis; Abdalhakam, Ibrahem; Farooq, Faisal; Taheri, Shahrad; Abou-Samra, Abdul Badi... more authors ... less authors ( Springer Nature , 2023 , Article)Objectives: To examine the hypothesis that obesity complicated by the metabolic syndrome, compared to uncomplicated obesity, has distinct molecular signatures and metabolic pathways. Methods: We analyzed a cohort of 39 ... -
Metabolic aspects of surgical subcutaneous fat removal: an umbrella review and implications for future research.
Badran, Saif; Doi, Suhail A; Hamdi, Moustapha; Hammouda, Atalla; Alharami, Sara; Clark, Justin; Musa, Omran A H; Abou-Samra, Abdul-Badi; Habib, Abdella M... more authors ... less authors ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2022 , Article Review)Although obesity is a preventable disease, maintaining a normal body weight can be very challenging and difficult, which has led to a significant increase in the demand for surgical subcutaneous fat removal (SSFR) to improve ... -
Metabolic changes after surgical fat removal: A dose–response meta-analysis
Saif, Badran; Habib, Abdella M.; Aljassem, Ghanem; Musa, Omran A.H.; Clark, Justin; Hamdi, Moustapha; Abou-Samra, Abdul-Badi; Glass, Graeme E.; Doi, Suhail A.... more authors ... less authors ( Elsevier , 2023 , Article Review)BackgroundBariatric surgery averts obesity-induced insulin resistance and the metabolic syndrome. By contrast, surgical fat removal is considered merely an esthetic endeavor. The aim of this article was to establish whether ... -
Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women.
Musa, Omran A H; Syed, Asma; Mohamed, Aisha M; Chivese, Tawanda; Clark, Justin; Furuya-Kanamori, Luis; Xu, Chang; Toft, Egon; Bashir, Mohammed; Abou-Samra, Abdul Badi; Thalib, Lukman; Doi, Suhail A... more authors ... less authors ( Elsevier , 2021 , Article)The comparative efficacy of gestational diabetes (GDM) treatments lack conclusive evidence for choice of first-line treatment. The aim of this study was to compare the efficacy of metformin and glibenclamide to insulin ... -
Unifying the diagnosis of gestational diabetes mellitus: Introducing the NPRP criteria
Suhail A.R., Doi; Bashir, Mohammed; Sheehan, Michael T.; Onitilo, Adedayo A.; Chivese, Tawanda; Ibrahim, Ibrahim M.; Beer, Stephen F.; Furuya-Kanamori, Luis; Abou-Samra, Abdul-Badi; McIntyre, H. David... more authors ... less authors ( Elsevier , 2021 , Article)AimsDisagreement about the appropriate criteria for the diagnosis of gestational diabetes mellitus (GDM) persists. This study examines an alternative approach which combines information from all time-points on the glucose ...