Browsing Medicine Research by Title
Now showing items 695-714 of 1314
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Interleukin-4 and interleukin-13 evoke scratching behaviour in mice
( Blackwell Publishing Ltd , 2019 , Article)Persistent and relapsing itch commonly manifests in inflammatory skin disorders such as atopic dermatitis (AD). AD pathogenesis is driven by interleukin-4 (IL-4) and interleukin-13 (IL-13). Dupilumab, a monoclonal antibody ... -
Interrelation between Sleep Bruxism and Obstructive Sleep Apnea: Literature Review
( Hooghly Sciencedomain International , 2021 , Article Review)Obstructive sleep apnea (OSA) is a clinical risk factor for sleep bruxism (SB). Although no clear causative link has been defined, both conditions are inter related to sleep-related arousal reactions. A literature review ... -
Interruption of perivascular and perirenal adipose tissue thromboinflammation rescues prediabetic cardioautonomic and renovascular deterioration
( Portland Press Ltd , 2024 , Article)The cardiovascular and renovascular complications of metabolic deterioration are associated with localized adipose tissue dysfunction. We have previously demonstrated that metabolic impairment delineated the heightened ... -
Intersection between genes controlling vascularization and angiogenesis in renal cell carcinomas
( Springer Nature , 2018 , Article)To show that application of the systemic analysis may significantly improve comparison of different datasets. Different genes and proteins may converge on the same functional outputs. A comparison of 2 datasets by only ... -
Intersectionality and Femicide: Palestinian Women's Experiences With the Murders of Their Beloved Female Relatives
( SAGE , 2021 , Article)This article examines how the intersectionality between political, socio-cultural, and demographic factors influences femicide events and women's experiences in Gaza. Based on the testimonies of 13 female first-degree ... -
Intestinal obstruction caused by a clamped persistent omphalomesenteric duct in congenital hernia into the umbilical cord.
( Wiley , 2021 , Article)A congenital hernia into the umbilical cord (CHUM) is often misinterpreted as a mild form of omphalocele. Herniated content in CHUM can be either the solitary intestinal loop or persistent omphalomesenteric duct (POMD) ... -
Intravenous fluids in hot pre-hospital environments: Thermal and physical stability of normal saline after exposure to simulated stress conditions
( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: Normal saline 0.9 % (NS) is the most widespread crystalloid used as a life-saving intravenous (IV) fluid. 1 NS contains sodium and chloride in equal concentrations and is subject to thermal stress conditions ... -
An Introduction to the Special Issue “Protein Glycation in Food, Nutrition, Health and Disease”
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Other)On 20–24 September 2021, leading researchers in the field of glycation met online at the 14th International Symposium on the Maillard Reaction (IMARS-14), hosted by the authors of this introductory editorial, who are from ... -
Investigating the blood-host plasticity and dispersal of Anopheles coluzzii using a novel field-based methodology
( BioMed Central Ltd. , 2019 , Article)Background: The biting behaviour and dispersal of insect vectors in the field underlies the transmission of many diseases. Here, a novel collection methodology coupled with the molecular analysis of blood-meal sources and ... -
An Investigation into the Association Between Inflammatory Bowel Disease and Cardiac Arrhythmias: An Examination of the United States National Inpatient Sample Database
( SAGE Publications , 2020 , Article)Background: Inflammatory bowel diseases (IBD) associated-chronic inflammation and autonomic dysregulation may predispose to arrhythmias. However, its exact prevalence is unknown. Thus, we aimed to ascertain the prevalence ... -
An investigation into the avoidability of adverse drug reactions using the LAAT and modified Hallas tools
( Wolters Kluwer Health , 2020 , Article)An adverse drug reactions avoidability tool called the Liverpool ADR avoidability assessment tool (LAAT) was recently developed (for research purposes), and subsequently validated with mixed interrater reliability (IRR). ... -
An investigation into the avoidability of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome
( Springer Nature , 2021 , Article)Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rising morbidity amongst hospitalized patients. Whilst clinical protocols for the management of individual DRESS cases have been well established, ... -
An investigation into the impact of enteric coated of aspirin in patients with newly diagnosed ischemic stroke (ECASIS)
( Wolters Kluwer Health , 2020 , Article)Introduction:Uncertainty remains regarding the impact of enteric-coated (EC) aspirin as it relates to the reduction of cardiovascular risk. We hypothesize that EC formulation based on a previous report may blunt aspirin ... -
An investigation of endometrial vascularity in normally menstruating women and those in other physiological states using 3D ultrasound imaging
( Wiley-Blackwell , 2024 , Article)Objectives: This study aimed to determine the normal vasculature indices of the endometrium and to correlate them with those in various physiological states. Methods: Women undergoing ultrasound at the Feto-Maternal Center, ... -
Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
( MDPI , 2022 , Article)(1) Background: Chronic myeloid leukemia is defined as the neoplastic development of mostly myeloid cells in the bone marrow. Several treatments, including chemotherapy, radiation, hormone treatment, and immunological ... -
Involvement of caveolae in hyperglycemia-induced changes in adiponectin and leptin expressions in vascular smooth muscle cells
( Elsevier , 2021 , Article)Hyperglycemia exerts various harmful effects on the vasculature. Studies have shown an association between the levels of the adipokines leptin and adiponectin (APN) and vascular complications in diabetes mellitus. The aim ... -
IP3 receptors and their intimate liaisons
( Elsevier , 2020 , Article Review)Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels. They allow cell-surface receptors that stimulate IP3 formation to evoke rapid Ca2+ release from the endoplasmic reticulum (ER). IP3Rs initiate ... -
IP3 receptors: An "elementary" journey from structure to signals
( Elsevier , 2023 , Article)Inositol 1,4,5-trisphosphate receptors (IP3Rs) are large tetrameric channels which sit mostly in the membrane of the endoplasmic reticulum (ER) and mediate Ca2+ release from intracellular stores in response to extracellular ... -
Is medical training solely to blame? Generational influences on the mental health of our medical trainees
( Taylor & Francis , 2024 , Article)Introduction: The negative impact of medical training on trainee mental health continues to be a concern. Situated within a sociocultural milieu, Generation Z and Generation Y, defined by their highly involved parents and ... -
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
( Taylor & Francis , 2019 , Article)Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize that the ...