تصفح Medicine Research حسب النوع "Book chapter"

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    • Apocrine Carcinoma 

      Vranic, Semir; Gatalica, Zoran ( Springer , 2020 , Book chapter)
      Carcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine ...

    • Apocrine Carcinoma 

      Vranic, Semir; Gatalica, Zoran ( Springer, Cham , 2017 , Book chapter)
      Carcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine cells” ...

    • Autism and the Scaffolding Protein Neurobeachin 

      Mohammed, Sawsan; Qoronfleh, M. Walid ( Springer , 2022 , Book chapter)
      Autism is a group of early onsets, diverse, lifelong, neurodevelopmental conditions that affect social interaction, verbal and non-verbal communications as well as behavior. It is a multifactorial condition, which results ...

    • Carcinoma with apocrine differentiation 

      Provenzano, E; Gatalica, Z; Vranic, S ( World Health Organization , 2019 , Book chapter)
      Carcinoma with apocrine differentiation is a rare subtype constituting ~1% of all invasive breast carcinomas. Patients tend to be older compared with patients with invasive breast carcinomas NST. Essential criteria: Invasive ...

    • Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET. 

      Nagi, Karim; Shenoy, Sudha K ( Humana Press, New York, NY , 2019 , Book chapter)
      Ubiquitination of G protein-coupled receptors (GPCRs) is an important dynamic posttranslational modification that has been linked to the intracellular trafficking of internalized GPCRs to lysosomes. Ubiquitination of GPCRs ...

    • DNA Damage/Repair Management in Cancers 

      Alhmoud, Jehad F.; Woolley, John F.; Al Moustafa, Ala-Eddin; Malki, Mohammed Imad ( Routledge , 2021 , Book chapter)
      DNA damage can alter nucleotide sequences and lead to expression of dysfunctional proteins that impact normal cellular physiology. Sources of DNA damage can be endogenous or exogenous and include reactive oxygen species ...

    • E-cadherin/catenin complex modulations in human oral cancer 

      Al Moustafa, Ala Eddin; Yasmeen, Amber ( Springer Netherlands , 2015 , Book chapter)
      Oral cancer is a common neoplasm in both male and female worldwide; the incidence and mortality of this cancer have increased over the past decades. Cancer metastasis is a major cause of morbidity and mortality in oral ...

    • High-risk human papillomaviruses and epstein-barr virus presence and crosstalk in human oral carcinogenesis 

      Al Moustafa, Ala Eddin; Cyprian, Farhan S.; Al-Antary, Noor; Yasmeen, Amber ( Springer International Publishing , 2017 , Book chapter)
      Oral cancer is the most frequent type of malignancy of the head and neck area worldwide. This cancer is a major cause of mortality in several parts of the world especially in certain Asian countries. In fact, the majority ...

    • Immunohistochemistry-Enabled Precision Medicine 

      Gatalica, Zoran; Feldman, Rebecca; Vranic, Semir; Spetzler, David ( Springer, Cham , 2019 , Book chapter)
      Immunohistochemistry (IHC) can be applied to diagnostic aspects of pathologic examination to provide aid in assignment of lineage and histologic type of cancer. Increasingly, however, IHC is widely used to provide prognostic ...

    • Neisseria gonorrhoeae Ketol-Acid Reductoisomerase Is a Potential Therapeutic Target 

      Rigane, Emna; Zughaier, Susu M ( IntechOpen , 2022 , Book chapter)
      The host-adapted human pathogen Neisseria gonorrhoeae is the causative agent of sexually transmitted infection gonorrhea. The increased emergence of gonorrhea infections worldwide, associated with the surging resistance ...

    • Oral Vaccine Delivery: The Coming Age of Particulate Vaccines to Elicit Mucosal Immunity 

      Gala, Rikhav P.; Bajaj, Lotika; Bansal, Amit; Gomes, Keegan Braz; Joshi, Devyani; ... more authors ( Springer , 2020 , Book chapter)
      With the evolution of different challenging diseases, there is an urgent need of vaccine development against them to save millions of lives around the world. Particlulate delivery system plays an important role by acting ...

    • Pediatric sleep disorders 

      Ather, Muhammed; Hashemi, Nehdia; Malik, Salma; Latif, Finza; Al-Breiki, Mohammed; ... more authors ( Nova Science Publishers, Inc. , 2022 , Book chapter)
      Patterns of normal sleep are considered, including the circadian cycle, which is considered the body's internal clock, REM, and NREM sleep. Sleep disorders are a prevalent problem in the pediatric population, affecting ...

    • Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Alzheimer’s Disease? 

      Reslan, Mohammad Amine; Issa, Hawraa; Al-Haj, Nadine; Ibeh, Stanley; Yehya, Yara; ... more authors ( Springer Singapore , 2022 , Book chapter)
      Alzheimer’s disease (AD) is a debilitating neurodegenerative disease with devastating outcomes to patients and exhaustive burdens to healthcare systems. Alzheimer’s disease has always been the focus of extensive research ...

    • Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Traumatic Brain Injury? 

      Al-Haj, Nadine; Issa, Hawraa; El Zein, Ola; Ibeh, Stanley; Reslan, Mohammad Amine; ... more authors ( Springer Singapore , 2022 , Book chapter)
      Traumatic brain injury (TBI) is one of the key causes of deaths and disabilities worldwide. TBI progresses in two phases. The primary phase of injury is the direct result of the physical damage caused by the external force ...

    • Prevention of oral cancer 

      Malki, Ahmed Mohamed; Raad, Samira Bou; Abu-El-Ruz, Rasha ( Springer International Publishing , 2017 , Book chapter)
      Oral cancer has become a major debilitating incidence in both genders alike. Oral cancer, a part of head and neck cancer, is a combination of two types of cancer: oral cavity cancer and oropharyngeal cancer. The most common ...

    • Psychosocial treatments for substance use disorders 

      Ather, Muhammad; Hashemi, Nehdia; Nazeer, Ahsan; Azeem, Muhammad Waqar ( Nova Science Publishers, Inc. , 2022 , Book chapter)
      Worldwide use of illicit drugs is increasing, and substance use disorders (SUDs) have become a significant mental health problem in the West. Although the majority of young people do not use illicit drugs and of those who ...

    • Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production 

      Galal, Youssef; Zaravinos, Apostolos; Bonavida, Benjamin ( Elsevier , 2021 , Book chapter)
      RKIP (Raf kinase inhibitory protein) is a metastatic suppressor and a chemo-immuno-sensitizer. The deficiency or loss of RKIP has been linked with different cancer types, resulting in the activation of the MAPK pathway, ...

    • Retinoids and Reactive Oxygen Species in Cancer Cell Death and Therapeutics 

      El-Baba, Chirine; Eid, Ali H.; Shaito, Abdallah; Kobeissy, Firas; Darwiche, Nadine ( Springer Nature , 2022 , Book chapter)
      Retinoids are a large family of structurally related natural and synthetic molecules that exhibit a variety of effects in embryogenesis and adult life. The parent compound of retinoids is vitamin A which was first discovered ...

    • RKIP in human diseases and its potential as a prognostic indicator and therapeutic target 

      Christofi, Theodoulakis; Zaravinos, Apostolos ( Elsevier , 2020 , Book chapter)
      The Raf kinase inhibitory protein (RKIP) is an inhibitor of the RAF/MEK/ERK and NF-κB signaling pathways, through which it regulates several key processes of the cell's physiology, such as its proliferation, motility and ...

    • Role of Qat chewing and mate consumption in human oral carcinogenesis 

      Kassab, Amal; Al Moustafa, Ala Eddin ( Springer International Publishing , 2017 , Book chapter)
      [No abstract available]