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Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice
(
Elsevier
, 2020 , Article)
Background and Objectives
In clinical trials, the relative risk or risk ratio (RR) is a mainstay of reporting of the effect magnitude for an intervention. The RR is the ratio of the probability of an outcome in an ...
Data extraction error in pharmaceutical versus non-pharmaceutical interventions for evidence synthesis: Study protocol for a crossover trial
(
Elsevier
, 2023 , Article)
BackgroundData extraction is the foundation for research synthesis evidence, while data extraction errors frequently occur in the literature. An interesting phenomenon was observed that data extraction error tend to be ...
Influence of lack of blinding on the estimation of medication-related harms: a retrospective cohort study of randomized controlled trials.
(
Springer Nature
, 2024 , Article)
Empirical evidence suggests that lack of blinding may be associated with biased estimates of treatment benefit in randomized controlled trials, but the influence on medication-related harms is not well-recognized. We aimed ...