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Macrophage responses associated with COVID-19: A pharmacological perspective
(
Elsevier
, 2020 , Article)
COVID-19 has caused worldwide death and economic destruction. The pandemic is the result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has demonstrated high rates of infectivity leading to great ...
Adipose tissue immunomodulation: A novel therapeutic approach in cardiovascular and metabolic diseases
(
Frontiers Media
, 2020 , Article)
Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As the main storage pool of lipids, ...
Recent advances in nanotherapeutics for multiple myeloma
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Anticancer therapies cannot be included in a one-size-fits-all scenario; it is imperative to adapt therapies to the tumor molecular profile and most importantly to develop target-specific therapeutics. Nanotherapeutics can ...
Covid-19 in pediatric patients: A focus on CHD patients
(
Frontiers Media S.A.
, 2020 , Article)
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease ...
Hydroxychloroquine in COVID-19 Patients: Pros and Cons
(
Frontiers Media S.A.
, 2020 , Article)
The pandemic of COVID-19, caused by SARS-CoV-2, has recently overwhelmed medical centers and paralyzed economies. The unparalleled public distress caused by this pandemic mandated an urgent quest for an effective approach ...
Worsening baroreflex sensitivity on progression to type 2 diabetes: Localized vs. systemic inflammation and role of antidiabetic therapy
(
American Physiological Society
, 2020 , Article)
Cardiac autonomic neuropathy (CAN) is an early cardiovascular manifestation of type 2 diabetes (T2D) that constitutes an independent risk factor for cardiovascular mortality and morbidity. Nevertheless, its underlying ...
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2020 , Article)
Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell colony-enhancing factor but turned out to possess enzymatic functions ...