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Use of conditional estimates of effect in cancer epidemiology: An application to lung cancer treatment
(
Elsevier
, 2024 , Article)
Background: In oncology clinical trials, there is the assumption that randomization sufficiently balances confounding covariates and therefore average treatment effects are usually reported. This paper explores the wider ...
Influence of lack of blinding on the estimation of medication-related harms: a retrospective cohort study of randomized controlled trials.
(
Springer Nature
, 2024 , Article)
Empirical evidence suggests that lack of blinding may be associated with biased estimates of treatment benefit in randomized controlled trials, but the influence on medication-related harms is not well-recognized. We aimed ...
Comparison of bias adjustment in meta-analysis using data-based and opinion-based methods.
(
Wolters Kluwer Health
, 2024 , Article)
Several methods exist for bias adjustment of meta-analysis results, but there has been no comprehensive comparison with unadjusted methods. We compare 6 bias-adjustment methods with 2 unadjusted methods to examine how these ...