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Targeting DNA Repair Pathways in Hematological Malignancies.
(
MDPI
, 2020 , Article Review)
DNA repair plays an essential role in protecting cells that are repeatedly exposed to endogenous or exogenous insults that can induce varying degrees of DNA damage. Any defect in DNA repair mechanisms results in multiple ...
Breath biopsy, a novel technology to identify head and neck squamous cell carcinoma: A systematic review
(
Wiley
, 2022 , Article Review)
Head and neck cancers are a heterogeneous group of neoplasms, which together comprise the sixth most common cancer globally. Breath biopsies are a non-invasive clinical investigation that detect volatile organic compounds ...
Clinical Implications of COVID-19 Presence in CSF: Systematic Review of Case Reports
(
MDPI
, 2022 , Article Review)
This systematic review focused on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients that had detected SARS-CoV-2 virus in cerebrospinal fluid (CSF). A systematic literature search was carried out in ...
DNA Damage/Repair Management in Cancers
(
MDPI
, 2020 , Article Review)
DNA damage is well recognized as a critical factor in cancer development and progression. DNA lesions create an abnormal nucleotide or nucleotide fragment, causing a break in one or both chains of the DNA strand. When DNA ...
The Role of CCL21/CCR7 Chemokine Axis in Breast Cancer Progression
(
MDPI
, 2015 , Article Review)
Tumor-induced lymphangiogenesis facilitates breast cancer progression by generating new lymphatic vessels that serve as conduits for tumor dissemination to lymph nodes and beyond. Given the recent evidence suggesting the ...
Emerging roles of activating transcription factor 2 in the development of breast cancer: a comprehensive review.
(
Oxford University Press
, 2023 , Article Review)
Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins that are responsible for regulating various genes that play an essential role in major biological and cellular ...
Metabolic-associated fatty liver disease: a selective review of pathogenesis, diagnostic approaches, and therapeutic strategies.
(
Frontiers Media
, 2024 , Article Review)
Metabolic associated fatty liver disease (MAFLD) is a novel terminology introduced in 2020 to provide a more accurate description of fatty liver disease associated with metabolic dysfunction. It replaces the outdated term ...