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Now showing items 11-20 of 43
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
(
Taylor & Francis
, 2019 , Article)
Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize that the ...
Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta-analysis of randomized controlled trials.
(
Wiley
, 2019 , Article Review)
Previous randomized and observational studies on the efficacy of metformin in pregnancy to reduce incident gestational diabetes mellitus (GDM) in women at high risk (obesity, polycystic ovary syndrome [PCOS], or pregestational ...
A proposed framework to guide evidence synthesis practice for meta-analysis with zero-events studies
(
Elsevier
, 2021 , Article)
ObjectiveIn evidence synthesis practice, researchers often face the problem of how to deal with zero-events. Inappropriately dealing with zero-events studies may lead to research waste and mislead healthcare practice. We ...
Sedentary Behavior, Physical Activity, and All-Cause Mortality: Dose-Response and Intensity Weighted Time-Use Meta-analysis.
(
Elsevier
, 2019 , Article)
Previous studies have placed those with excessive sedentary behavior at increased risk of all-cause mortality. There is evidence of interdependency of sedentary behavior with physical activity, and its elucidation will ...
Physical activity in pregnancy prevents gestational diabetes: A meta-analysis
(
Elsevier
, 2020 , Article)
AimsThe effectiveness of physical activity (PA) programs for prevention of gestational diabetes (GDM) lacks conclusive evidence. The aim of this study was to generate clear evidence regarding the effectiveness of physical ...
Selecting the best meta-analytic estimator for evidence-based practice: a simulation study.
(
Lippincott, Williams & Wilkins
, 2019 , Article)
Studies included in meta-analysis can produce results that depart from the true population parameter of interest due to systematic and/or random errors. Synthesis of these results in meta-analysis aims to generate an ...
A new improved graphical and quantitative method for detecting bias in meta-analysis.
(
Lippincott, Williams & Wilkins
, 2018 , Article)
Detection of publication and related biases remains suboptimal and threatens the validity and interpretation of meta-analytical findings. When bias is present, it usually differentially affects small and large studies ...
Utilization of the evidence from studies with no events in meta-analyses of adverse events: an empirical investigation
(
Springer
, 2021 , Article)
Zero-events studies frequently occur in systematic reviews of adverse events, which consist of an important source of evidence. We aimed to examine how evidence of zero-events studies was utilized in the meta-analyses of ...
Evaluation of Gender Inequity in Thyroid Cancer Diagnosis: Differences by Sex in US Thyroid Cancer Incidence Compared with a Meta-analysis of Subclinical Thyroid Cancer Rates at Autopsy
(2021 , Article)
Importance: Thyroid cancer is more common in women than in men, but the associated causes of these differences are not fully understood. Objective: To compare sex-specific thyroid cancer rates in the US to the prevalence ...
Unifying the diagnosis of gestational diabetes mellitus: Introducing the NPRP criteria
(
Elsevier
, 2021 , Article)
AimsDisagreement about the appropriate criteria for the diagnosis of gestational diabetes mellitus (GDM) persists. This study examines an alternative approach which combines information from all time-points on the glucose ...