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Lichen planus: a comprehensive evidence-based analysis of medical treatment
(
Blackwell Publishing Ltd
, 2019 , Article Review)
Lichen planus (LP) is a chronic-relapsing inflammatory skin disease. Although many drugs have been used for the management of LP, some of them lack the backup by strong therapeutic evidence, while others are not suitable ...
Somatostatin receptor SSTR2A and SSTR5 expression in neuroendocrine breast cancer.
(
Elsevier
, 2019 , Article)
Neuroendocrine breast cancer (NEBC) is a group of rare tumors, which could benefit from therapy targeting the somatostatin receptors (SSTRs). In particular, SSTR2A and SSTR5 are potential targets given their consistent ...
Molecular profiling reveals novel targetable biomarkers in neuroendocrine carcinoma of the uterine cervix
(
Oxford University Press
, 2019 , Conference Paper)
Background
Neuroendocrine carcinoma of the uterine cervix (NEC) is a rare cervical malignancy, accounting for 0.9% of all cervical carcinomas. Cervical NEC is a high-grade cancer with an aggressive clinical course and ...
Development of discriminant functions to estimate sex in upper limb bones for mixed ancestry South Africans
(
Elsevier
, 2019 , Article)
The Chartered Society of Forensic Sciences South Africa has one of the highest murder rates in the world, which is associated with an increasing number of unidentified individuals. Forensic anthropologists can assist in ...
Safety and efficacy of leadless pacemaker retrieval
(
Blackwell Publishing Inc.
, 2019 , Article Review)
Background and Objectives: The success rate of leadless cardiac pacemaker (LP) retrieval remains a major concern for this disruptive technology. The present paper performed a systematic review of the safety and feasibility ...
Letter to Editor: Apocrine carcinoma is the fact. Comment on the recent paper entitled "Invasive apocrine carcinoma of the breast: Myth or fact?" by Gurrado et al (Breast J. 2019 Sep 8. doi: 10.1111/tbj.13569. [Epub ahead of print].
(
Wiley
, 2019 , Article)
The most recent WHO classification of breast cancer also recognizes the concept of “pure apocrine carcinoma” (called carcinoma with apocrine differentiation) with cancers having >90% of apocrine morphology (an essential ...
Using tibial fragments to reconstruct the total skeletal height of black South Africans
(
Elsevier
, 2019 , Article)
Stature is an important component of the biological profile of unknown skeletal remains and regression equations for estimating stature have been derived for a number of bones. However, bones are rarely recovered intact ...
Activation of K7 channels with the anticonvulsant retigabine alleviates neuropathic pain behaviour in the streptozotocin rat model of diabetic neuropathy.
(
Taylor & Francis (Routledge)
, 2019 , Article)
Diabetic peripheral neuropathy (DPN) is the most incapacitating complication of diabetes mellitus. Up to 50% of patients with DPN develop peripheral neuropathic pain (PNP). The underlying ionic and molecular mechanisms of ...
Immunohistochemistry-Enabled Precision Medicine
(
Springer, Cham
, 2019 , Book chapter)
Immunohistochemistry (IHC) can be applied to diagnostic aspects of pathologic examination to provide aid in assignment of lineage and histologic type of cancer. Increasingly, however, IHC is widely used to provide prognostic ...
Seasonality and community interventions in a mathematical model of Clostridium difficile transmission
(
W.B. Saunders Ltd
, 2019 , Article)
Background: Clostridium difficile infection (CDI)is the leading cause of antibiotic-associated diarrhoea with peak incidence in late winter or early autumn. Although CDI is commonly associated with hospitals, community ...