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Recent advances in targeting protein arginine methyltransferase enzymes in cancer therapy
(
Taylor and Francis Ltd
, 2018 , Article Review)
Introduction: Exploration in the field of epigenetics has revealed the diverse roles of the protein arginine methyltransferase (PRMT) family of proteins in multiple disease states. These findings have led to the development ...
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...
Curcumin-mediated degradation of S-phase kinase protein 2 induces cytotoxic effects in human papillomavirus-positive and negative squamous carcinoma cells
(
Frontiers Media S.A.
, 2018 , Article)
S-phase kinase-associated protein2 (Skp2), a proto-oncoprotein, plays an important role in development and progression of human malignancies. Skp2 is frequently overexpressed in many human malignancies. It targets cell ...
Signaling pathways activated by PACAP in MCF-7 breast cancer cells
(
Elsevier Inc.
, 2018 , Article)
PACAP has opposing roles ranging from activation to inhibition of tumor growth and PACAP agonists/antagonists could be used in tumor therapy. In this study, the effect of PACAP stimulation on signaling pathways was ...
Carbon nanotubes: Applications in cancer therapy and drug delivery research
(
Elsevier
, 2018 , Book chapter)
Carbon nanotubes (CNTs) are novel nanocarrier systems that have a wide range of applications in science, engineering, and, the environment. Owing to the possible functionalization of CNTs (i.e., surface-engineering of the ...