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Now showing items 11-20 of 20
Water-pipe smoking promotes epithelial-mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways.
(
BioMed Central Ltd.
, 2018 , Article)
With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women's health. The main goal of this study is to identify the potential outcome of WPS on human breast cancer ...
Investigation of the effect of PD-L1 blockade on triple negative breast cancer cells using fourier transform infrared spectroscopy
(
MDPI AG
, 2019 , Article)
Interactions between programmed death-1 (PD-1) with its ligand PD-L1 on tumor cells can antagonize T cell responses. Inhibiting these interactions using immune checkpoint inhibitors has shown promise in cancer immunotherapy. ...
Developing a risk prediction model for breast cancer: A Statistical Utility to Determine Affinity of Neoplasm (Sudan-CA Breast)
(
BioMed Central Ltd.
, 2017 , Article)
Background: Breast cancer risk prediction models are widely used in clinical settings. Although most of the well-known models were designed based on data collected from western population, yet they have been utilized for ...
Gene expression and miRNAs profiling: Function and regulation in human epidermal growth factor receptor 2 (HER2) - positive breast cancer
(
MDPI AG
, 2019 , Article)
Breast cancer is the second most common cause of cancer-related deaths among women worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the subtypes, human epidermal growth factor receptor 2 ...
A prospective investigation of oral contraceptive use and breast cancer mortality: findings from the Swedish women's lifestyle and health cohort.
(
BMC
, 2019 , Article)
The association between oral contraceptive (OC) use and long-term mortality remains uncertain and previous studies have reported conflicting findings. We aim to assess the long-term impact of OC use on all-cause and ...
Acquisition of invasiveness by breast adenocarcinoma cells engages established hallmarks and novel regulatory mechanisms
(
International Institute of Anticancer Research
, 2019 , Article)
Background/Aim: Proteomics of invasiveness opens a window on the complexity of the metastasis-engaged mechanisms. The extend and types of this complexity require elucidation. Materials and Methods: Proteomics, immuno ...
A simple model for cell type recognition using 2D-correlation analysis of FTIR images from breast cancer tissue
(
Elsevier B.V.
, 2018 , Article)
Breast cancer is the second most common cancer after lung cancer. So far, in clinical practice, most cancer parameters originating from histopathology rely on the visualization by a pathologist of microscopic structures ...
PD-L1 status in breast cancer: Current view and perspectives.
(
Elsevier
, 2019 , Article)
Breast cancer was traditionally not considered a particularly immunogenic tumor. However, recent developments have shown that some aggressive triple-negative breast cancers are immunogenic, exhibit a resistance to chemotherapy ...
Breast cancer image classification using pattern-based Hyper Conceptual Sampling method
(
Elsevier Ltd
, 2018 , Article)
The increase in biomedical data has given rise to the need for developing data sampling techniques. With the emergence of big data and the rise of popularity of data science, sampling or reduction techniques have been ...
Exposure to EGF and 17-estradiol irreversibly affects the proliferation and transformation of MCF7 cells but is not sufficient to promote tumor growth in a xenograft mouse model upon withdrawal of exposure
(
Spandidos Publications
, 2018 , Article)
Epidermal growth factor (EGF) and estrogen are potent regulators of breast tumorigenesis. Their short‑term actions on human breast epithelial cells have been investigated extensively. However, the consequence of a long‑term ...