تصفح Pharmacy Research حسب العنوان
السجلات المعروضة 1077 -- 1096 من 1188
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Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents
( Elsevier , 2022 , Article Review)Cancer is one of the leading causes of death and significantly burdens the healthcare system. Due to its prevalence, there is undoubtedly an unmet need to discover novel anticancer drugs. The use of natural products as ... -
Targeting dopaminergic system for treating nicotine dependence
( Bentham Science Publishers B.V. , 2016 , Article)Background: Smoking is the world's leading cause of preventable death among populations. Cigarette smoking increases the risk of numerous health problems, including heart diseases, stroke, atherosclerosis and many types ... -
Targeting Osteopontin, the Silent Partner of Na+/H+ Exchanger Isoform 1 in Cardiac Remodeling
( Wiley Periodicals, Inc. , 2015 , Article)Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, contributes to cardiac remodeling, which if left unresolved results in heart failure. Understanding the signaling pathways ... -
Taxane anticancer formulations: challenges and achievements
( Academic Press , 2020 , Book chapter)Taxanes represent a prominent anticancer family. Paclitaxel and docetaxel are the most well-known taxanes owing to their activity against many types of cancers. The poor solubility of taxanes in water is a major obstacle ... -
Taxane formulations: From plant to clinic
( Springer International Publishing , 2017 , Book chapter)Taxanes including paclitaxel and docetaxel are highly active against many types of cancers. The main obstacle with developing delivery systems of taxanes is their poor water solubility. In this chapter, taxanes were reviewed ... -
Teaching pharmacovigilance to undergraduate students: Our experience in poor-resource setting
( Wolters Kluwer Health , 2022 , Article)Using medicines associated with adverse drug reactions (ADRs) might cause serious health complications. The pharmacist plays a unique role in monitoring ADRs, either by themselves or with the assistance of other health-care ... -
Telephone versus office-based management of warfarin: Impact on international normalized ratios and outcomes
( Springer-Verlag Tokyo , 2014 , Article)Studies have concluded that telephone-based management of warfarin is an effective alternative to in-office management. High rates of patient and physician satisfaction have been reported with telephone-based monitoring. ... -
Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction
( Mary Ann Liebert, Inc. , 2017 , Article)Aims: Circulating microparticles (MPs) from metabolic syndrome patients and those generated from apoptotic T-cells induce endothelial dysfunction; however, the molecular and cellular mechanism(s) underlying in the effects ... -
The Arabic version of the sleep hygiene index: Linguistic validation and cultural adaptation among University students in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Introduction: Sleep is necessary for maintaining adequate health and well-being. However, several behavioral and environmental factors, known as sleep hygiene, could affect sleep quality, contributing to the development ... -
The Association Between Religiosity, Spirituality, and Medication Adherence Among Patients with Cardiovascular Diseases: A Systematic Review of the Literature
( Springer , 2022 , Article)This systematic review aimed to summarize the literature on the relationship between religiosity or spirituality (R/S) and medication adherence among patients with cardiovascular diseases (CVDs) and to describe the nature ... -
The Association between Zinc and Copper and Cardiometabolic Risk Factors in Adults
( Qatar University Press , 2021 , Poster)Cardiometabolic risk (CMR) factors increase the likelihood of developing cardiovascular diseases (CVD). In Qatar, 24% of the total deaths are attributed to CVDs. Several nutritional disturbances have been linked to high ... -
The development of a theory-informed Communities of Practice Framework for pharmacy and other professional healthcare education programmes
( International Pharmaceutical Federation , 2018 , Article)This paper describes the development of a novel Communities of Practice (CoP) theory-informed framework. The CoP framework, developed through a rigorous process of extensive review of the literature and peer review by ... -
The development, translation and validation of an instrument used in a tobacco cessation intervention study among patients with diabetes
( Asian Journal of Pharmaceutical and Clinical Research , 2014 , Article)Objective: In diabetes care, smoking cessation is a very important component that should be addressed in order to facilitate effective blood glucose control and to limit the development of complications associated with ... -
The Dilemma of Peri-Procedural Warfarin Management: A Narrative Review
( SAGE Publications Inc. , 2021 , Article Review)Periprocedural vitamin K antagonist management is a complex process and inherently entails multiple clinical issues. Marked variations have been reported in different aspects of this process. These differences were noted ... -
The Effect of CYP2C19 and Nongenetic Factors on Clopidogrel Responsiveness in the MENA Region: A Systematic Review
( SAGE Publications Inc. , 2019 , Article Review)Clopidogrel is the cornerstone antiplatelet used in the treatment and prevention of thrombotic events. Some studies examined the effect of CYP2C19 polymorphism and nongenetic factors on clopidogrel response in the Middle ... -
The effect of migration on the incidence of new-onset metabolic syndrome in migrants to Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: There is substantial evidence that migration to Western countries is associated with an increased risk of metabolic syndrome (MetS) 1 . However, there is a paucity of data on the incidence of MetS in migrants ... -
The effect of tailored consumer medicine information on patients with type 2 diabetes mellitus: A randomised controlled interventional study
( Blackwell Publishing Ltd , 2020 , Article)Introduction: In patients with diabetes, better health communication is associated with better health outcomes including medication adherence and glycaemic control. The conventional patient information leaflet does not ... -
The effectiveness and safety of palbociclib and ribociclib in stage IV HR+/HER-2 negative breast cancer: a nationwide real world comparative retrospective cohort study
( Frontiers Media SA , 2023 , Article)Introduction: Palbociclib and ribociclib are indicated in the first-line treatment of hormonal receptor-positive HER-2 negative (HR+/HER2- negative) advanced breast cancer. Although randomized-controlled trials (RCTs) ... -
The Effectiveness of Levosimendan on Veno-Arterial Extracorporeal Membrane Oxygenation Management and Outcome: A Systematic Review and Meta-Analysis
( Elsevier , 2021 , Article Review)Objectives: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides a temporary support system for patients with cardiogenic shock refractory to conventional medical therapies. It has been reported that ... -
The experiences of implementing generic medicine policy in eight countries: A review and recommendations for a successful promotion of generic medicine use
( Elsevier , 2014 , Article)Generic medicines are clinically interchangeable with original brand medicines and have the same quality, efficacy and safety profiles. They are, nevertheless, much cheaper in price. Thus, while providing the same therapeutic ...
