Browsing Pharmacy Research by Subject "cardiovascular disease"
Now showing items 1-9 of 9
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Cost-Effectiveness of Empagliflozin and Metformin Combination Versus Standard Care as First-Line Therapy in Patients With Type 2 Diabetes Mellitus
( Elsevier , 2022 , Article)ObjectiveSodium-glucose cotransporter 2 inhibitors have been shown to reduce cardiovascular events but are currently not used as the first-line therapy. This study was conducted to evaluate the cost-effectiveness of ... -
Endoplasmic Reticulum (ER) Stress-Generated Extracellular Vesicles (Microparticles) Self-Perpetuate ER Stress and Mediate Endothelial Cell Dysfunction Independently of Cell Survival.
( Frontiers Media , 2020 , Article)Circulating extracellular vesicles (EVs) are recognized as biomarkers and effectors of endothelial dysfunction, the initiating step of cardiovascular abnormalities. Among these EVs, microparticles (MPs) are vesicles directly ... -
Evaluation of cardiovascular risk in adult psychiatric outpatients in Qatar using two risk assessment tools
( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Introduction: Individuals with serious mental illness (SMI) experience premature death, likely due to increased rates of obesity and cardiovascular disease (CVD). This study was conducted to estimate the CVD risk in a ... -
Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction
( MDPI , 2020 , Article)Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at ... -
Role of pharmacist in cardiovascular disease-related health promotion and in hypertension and dyslipidemia management: A cross-sectional study in the State of Qatar
( Blackwell Publishing Ltd , 2016 , Article)Rationale, aims and objectives In Qatar, cardiovascular diseases (CVD) have recently become the leading cause of morbidity and mortality. Prevention, detection and management of CVD risk factors reduce CVD chance. The study ... -
The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance.
( MDPI , 2019 , Article Review)Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ... -
Sestrin2 as a Protective Shield against Cardiovascular Disease
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)A timely and adequate response to stress is inherently present in each cell and is important for maintaining the proper functioning of the cell in changing intracellular and extracellular environments. Disruptions in the ... -
Societal health and economic burden of cardiovascular diseases in the population with type 2 diabetes in Qatar. A 10-year forecasting model
( Wiley-Blackwell , 2023 , Article)Aims: To predict the future health and economic burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) in Qatar. Materials and Methods: A dynamic multistate model was designed to simulate the progression of fatal ... -
What Are the Challenges in Conducting Cost-of-Illness Studies?
( Elsevier Inc. , 2014 , Article)[No abstract available]