Browsing Mechanical & Industrial Engineering by Author "Jaffa M.A."
Now showing items 1-3 of 3
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Modulation of proteomic and inflammatory signals by Bradykinin in podocytes
Saoud R.; Jaffa M.A.; Habib A.; Zhao J.; Al Hariri M.; Zhu R.; Hasan, Anwarul; Ziyadeh F.N.; Kobeissy F.; Mechref Y.; Jaffa A.A.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Podocyte damage is one of the hallmarks of diabetic nephropathy leading to proteinuria and kidney damage. The underlying mechanisms of podocyte injury are not well defined. Bradykinin (BK) was shown to contribute to diabetic ... -
Sulfated alginate/polycaprolactone double-emulsion nanoparticles for enhanced delivery of heparin-binding growth factors in wound healing applications
Maatouk B.; Jaffa M.A.; Karam M.; Fahs D.; Nour-Eldine W.; Hasan, Anwarul; Jaffa A.A.; Mhanna R.... more authors ... less authors ( Elsevier B.V. , 2021 , Article)Diabetic foot ulcers (DFUs) that are not effectively treated could lead to partial or complete lower limb amputations. The lack of connective tissue growth factor (CTGF) and insulin-like growth factor (IGF-I) in DFUs results ... -
Vascular cells proteome associated with bradykinin and leptin inflammation and oxidative stress signals
Hariri M.A.; Jaffa M.A.; Saoud R.; Zhao J.; Zhu R.; Jaffa A.A.; El-Achkar G.A.; Moussa M.; Kobeissy F.; Hassan A.; Ziyadeh F.N.; Mechref Y.; Jaffa A.A.... more authors ... less authors ( MDPI , 2020 , Article)Among the primary contributors to cardiovascular diseases are inflammation and oxidative imbalance within the vessel walls as well as the fibrosis of rat aortic smooth muscle cell (RASMC). Bradykinin (BK) and leptin are ...