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Spatial mapping of cancer tissues by OMICS technologies
(
Elsevier B.V.
, 2022 , Article)
Spatial mapping of heterogeneity in gene expression in cancer tissues can improve our understanding of cancers and help in the rapid detection of cancers with high accuracy and reliability. Significant advancements have ...
Characterization and In vitro biocompatibility analysis of nanocellulose scaffold for tissue engineering application
(
Springer Science and Business Media B.V.
, 2022 , Article)
Tissue engineering aims to exploit the regenerative capacity of cells and connect the inherent ability of the body to repair and regenerate. Cells are seeded onto a porous three-dimensional scaffold in tissue engineering, ...
Halloysite nanotube and chitosan polymer composites: Physicochemical and drug delivery properties
(
Editions de Sante
, 2022 , Article)
Advancement in healthcare requires sophisticated and safe drug delivery systems. An ideal drug delivering system should be non-toxic, therapeutically inert, and be able to deliver a wide range of drugs. Here, we report ...
Nitric oxide-releasing biomaterials for promoting wound healing in impaired diabetic wounds: State of the art and recent trends
(
Elsevier Masson s.r.l.
, 2022 , Article)
Impaired diabetic wounds are serious pathophysiological complications associated with persistent microbial infections including failure in the closure of wounds, and the cause of a high frequency of lower limb amputations. ...
Exome sequencing of glioblastoma-derived cancer stem cells reveals rare clinically relevant frameshift deletion in MLLT1 gene
(
BioMed Central Ltd
, 2022 , Article)
Background: Glioblastoma multiforme (GBM) is a heterogeneous CNS neoplasm which causes significant morbidity and mortality. One reason for the poor prognostic outcome of GBM is attributed to the presence of cancer stem ...
Cisplatin encapsulated nanoparticles from polymer blends for anti-cancer drug delivery
(
Royal Society of Chemistry
, 2022 , Article)
Developing novel nanocarriers for anticancer drug delivery has become a ‘promising niche’. The toxicity of the carrier and its efficacy in treatment modalities have become cardinal points as they can impede the progress ...
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
(
Springer
, 2022 , Article)
Diabetes mellitus (DM)-induced cardiac morbidities have been the leading cause of death among diabetic patients. Recently, sodium-glucose cotransporter-2 (SGLT-2) inhibitors including empagliflozin (EMPA), which have been ...
Multifunctional Bioactive Scaffolds from ARX- g-(Zn@rGO)-HAp for Bone Tissue Engineering: In Vitro Antibacterial, Antitumor, and Biocompatibility Evaluations
(
American Chemical Society
, 2022 , Article)
Advanced biomaterials are required with enhanced antibacterial and anticancer activities to obtain desirable biocompatibility during and after scaffold implantation in tissue engineering. Here, we report the development ...
Bioactive scaffold (sodium alginate)-g-(nHAp@SiO2@GO) for bone tissue engineering
(
Elsevier
, 2022 , Article)
Globally, people suffering from bone disorders are steadily increasing and bone tissue engineering is an advanced approach to treating fractured and defected bone tissues. In this study, we have prepared polymeric nanocomposite ...
Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues
(
MDPI
, 2022 , Article Review)
Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at the single-cell level and possess an unprecedented potential for exploring signatures involved in tumor development and progression. ...