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Enzyme?polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms
(
Elsevier B.V.
, 2021 , Article)
Background: Because enzymes can control several metabolic pathways and regulate the production of free radicals, their simultaneous use with nanoplatforms showing protective and combinational properties is of great interest ...
Nanozyme-based sensing platforms for detection of toxic mercury ions: An alternative approach to conventional methods
(
Elsevier B.V.
, 2020 , Article)
Mercury (Hg) is known as a poisonous heavy metal which stimulates a wide range of adverse effects on the human health. Therefore, development of some feasible, practical and highly sensitive platforms would be desirable ...
Exploring the interaction of synthesized nickel oxide nanoparticles through hydrothermal method with hemoglobin and lymphocytes: Bio-thermodynamic and cellular studies
(
Elsevier B.V.
, 2020 , Article)
The NiO NPs were synthesized by hydrothermal method and their interaction with Hb was investigated by employing fluorescence, UV?vis absorption techniques as well as docking studies. Also, the cytotoxic impacts of NiO NPs ...
Enzyme immobilization onto the nanomaterials: Application in enzyme stability and prodrug-activated cancer therapy
(
Elsevier B.V.
, 2020 , Article)
Nanoparticles (NPs) have been widely used for immobilization of wide ranges of enzymes. However, the stabilization of enzymes on NPs is a major challenge, crucial for regulating enzymatic activity and their medical ...
Antioxidant properties of gold nanozyme: A review
(
Elsevier B.V.
, 2020 , Article)
AuNPs with enzyme-like features have received strong attention in different areas, although limited data is available in literature on their biological/industrial functions. NPs especially Au counterparts have been shown ...
Gold nanozyme: Biosensing and therapeutic activities
(
Elsevier Ltd
, 2020 , Article)
The utilization of AuNPs in therapeutic applications has been accelerated by discovering their catalytic activity consistent with the activity of natural enzymes. However, to reduce unwanted activities, it is imperative ...
Fabrication of inorganic alumina particles at nanoscale by a pulsed laser ablation technique in liquid and exploring their protein binding, anticancer and antipathogenic activities
(
Elsevier B.V.
, 2021 , Article)
The interaction of nanoparticles with biological systems can provide useful information about their therapeutic applications. The aluminum nanoparticles (Al2O3 NPs) were synthesized by laser ablation technique and ...
Polymeric-based microneedle arrays as potential platforms in the development of drugs delivery systems
(
Elsevier B.V.
, 2020 , Article)
Background: Microscopic patches as quite promising platforms in transdermal drug delivery suffer from conventional injections. In other hand, a wide range of pharmacokinetics, ranging from fast oral administration to ...
Hydrothermal method-based synthesized tin oxide nanoparticles: Albumin binding and antiproliferative activity against K562 cells
(
Elsevier Ltd
, 2021 , Article)
The interaction of nanoparticles with protein and cells may provide important information regarding their biomedical implementations. Herein, after synthesis of tin oxide (SnO2) nanoparticles by hydrothermal method, their ...
Thermodynamic and anticancer properties of inorganic zinc oxide nanoparticles synthesized through co-precipitation method
(
Elsevier B.V.
, 2021 , Article)
In this paper, inorganic zinc oxide nanoparticles (ZnO NPs) were synthesized through co-precipitation method and after evaluating their physicochemical properties by using TEM and XRD techniques, the bio-thermodynamic and ...