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Growth factor loaded in situ photocrosslinkable poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/gelatin methacryloyl hybrid patch for diabetic wound healing
(
Elsevier Ltd
, 2021 , Article)
Management of chronic diabetic ulcers remains as a major challenge in healthcare which requires extensive multidisciplinary approaches to ensure wound protection, management of excess wound exudates and promoting healing. ...
Cellular response to nanobiomaterials
(
Elsevier
, 2020 , Book chapter)
The application of nanobiomaterials in biomedical field is rapidly processing, especially in the areas where conventional approaches have limited success. Cell fate is mainly influenced by interactions between cells and ...
3D printed nanocomposites for tailored cardiovascular tissue constructs: A minireview
(
Elsevier B.V.
, 2021 , Article)
Cardiovascular diseases (CVD) with escalating death rates pose one of the greatest threats to global health and well-being. Thus, developing effective interventions to combat CVD are of critical importance. 3D printing ...
Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
(
Elsevier B.V.
, 2021 , Article)
Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ...
Application of gelatin nanoconjugates as potential internal stimuli-responsive platforms for cancer drug delivery
(
Elsevier B.V.
, 2020 , Article)
Nanoparticles (NPs) have been continuously utilized for different implementations, most particularly for cancer drug delivery. A large number of NP-based drug delivery systems (DDSs) have been explored for cancer therapy ...
Mucoadhesive chitosan derivatives as novel drug carriers
(
Bentham Science Publishers B.V.
, 2015 , Article)
Chitosan on its own is a well-established natural polymer and is widely regarded as a biodegradable, biocompatible and nontoxic material for drug delivery applications. Although unmodified chitosan has some mucoadhesive ...
Nanosilver loaded GelMA hydrogel for antimicrobial coating of biomedical implants
(
Institute of Electrical and Electronics Engineers Inc.
, 2015 , Conference Paper)
Bacterial adhesion to the surface of implants in surgical procedures represents a major problem in surgeries, as it incurs high medical costs and could lead to postoperative infections. Different strategies have been ...
Experimental studies and computer modeling of viscoelastic properties of heart valve leaflets: Implication in heart valve tissue engineering
(
Institute of Electrical and Electronics Engineers Inc.
, 2015 , Conference Paper)
Diseased or damaged heart valve leaflets are amongst the major causes of illness and death globally. The currently available treatment of heart valve patients is to mend the damaged valves, but in most severe cases, heart ...
Porcine cholecyst derived extracellular matrix (p-CEM) for reconstruction of full thickness skin wounds in rats
(
Elsevier GmbH
, 2015 , Article)
An acellular cholecyst derived extracellular matrix (p-CEM) of porcine origin was prepared using anionic biological detergent. Healing potential of (p-CEM) was compared with commercially available collagen sheet (b-CS) and ...
Bovine reticulum derived extracellular matrix (b-REM) for reconstruction of full thickness skin wounds in rats
(
Elsevier GmbH
, 2016 , Article)
Thirty six clinically healthy adult Wistar rats of either sex were used in the study and randomly divided into three groups having twelve animals in each group. Under general anesthesia, a full-thickness skin wound (20 ? ...