• The Three CARMA Sisters: So Different, So Similar: A Portrait of the Three CARMA Proteins and Their Involvement in Human Disorders 

      Scudiero, I.; Vito, P.; Stilo, R. ( Wiley Periodicals, Inc. , 2014 , Article)
      Initially identified by their ability to modulate the functional activity of BCL10, the three CARMA proteins, CARMA1, -2, and -3, have recently themselves taken a leading role on the stage of molecular medicine. Although ...
    • Thymus vulgaris (Thyme) inhibits proliferation, adhesion, migration, and invasion of human colorectal cancer cells 

      Al-Menhali, Afnan; Al-Rumaihi, Aisha; Al-Mohammed, Hana; Al-Mazrooey, Hana; Al-Shamlan, Maryam; ... more authors ( Mary Ann Liebert Inc. , 2015 , Article)
      Colorectal cancer (CRC) remains one of the most common malignancies and a leading cause of cancer-related deaths. Its prognosis remains poor for patients with several grades of this disease. This underscores the need for ...
    • Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk. 

      Bhat, Ajaz A; Uppada, Srijayaprakash; Achkar, Iman W; Hashem, Sheema; Yadav, Santosh K; ... more authors ( Frontiers Media , 2019 , Article)
      The ability of epithelial cells to organize through cell-cell adhesion into a functioning epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent cells are made up of tight junctions ...
    • Toads in Qatar: The species present and their probable original source 

      Nobuyuki, Yamaguchi; Vasconcelos, Raquel; Mohamed, Toqa; Abdel-Fattah Ahmed, Talaat; Alatalo, Juha Mikael; ... more authors ( Elsevier , 2019 , Article)
      Toads are likely to have been introduced to Qatar, but little information is available on toad populations in the country, including the species present and their probable origin. Therefore, we collected tissue samples for ...
    • Total Hg levels distribution in fish and fish products and their relationships with fish types, weights, and protein and lipid contents: A multivariate analysis 

      Al-Sulaiti, Maetha M.; Soubra, Lama; Ramadan, Gouda A.; Ahmed, Abdullah Qasem Saif; Al-Ghouti, Mohammad A. ( Elsevier , 2023 , Article)
      This study investigates the mercury (Hg) levels distribution in fish and fish products and their relationships with fish types, weights, protein, and lipid contents in Qatar. Principal component analysis (PCA) was employed ...
    • Towards Gas Hydrate-Free Pipelines: A Comprehensive Review of Gas Hydrate Inhibition Techniques 

      Elhenawy, Salma; Khraisheh, Majeda; Almomani, Fares; Al-Ghouti, Mohammad A.; Hassan, Mohammad K.; ... more authors ( MDPI , 2022 , Article Review)
      Gas hydrate blockage is a major issue that the production and transportation processes in the oil/gas industry faces. The formation of gas hydrates in pipelines results in significant financial losses and serious safety ...
    • Towards novel Cry toxins with enhanced toxicity/broader: a new chimeric Cry4Ba / Cry1Ac toxin 

      Zghal, Raida Zribi; Elleuch, Jihen; Ali, Mamdouh Ben; Darriet, Frederic; Rebaï, Ahmed; ... more authors ( Springer-Verlag , 2017 , Article)
      Attempts have been made to express or to merge different Cry proteins in order to enhance toxic effects against various insects. Cry1A proteins of Bacillus thuringiensis form a typical bipyramidal parasporal crystal and ...
    • Towards understanding the genetics of Autism 

      Shailesh, Harshita; Gupta, Ishita; Sif, Said; Ouhtit, Allal ( Frontiers in Bioscience , 2016 , Article Review)
      Autism spectrum disorder (ASD) includes a group of neurodevelopmental disorders that affect communication skills, social interaction and intellectual ability. Despite evidence suggesting a strong genetic link with ASD, the ...
    • Towards understanding the mechanisms of actions of carcinoembryonic antigen-related cell adhesion molecule 6 in cancer progression 

      Rizeq, Balsam; Zakaria, Zain; Ouhtit, Allal ( Wiley Open Access , 2017 , Article Review)
      Human carcinoembryonic antigen (CEA) is the prototypic member of a family of highly related cell surface glycoproteins that includes carcinoembryonic antigenrelated cell adhesion molecule 6 (CEACAM6) and others. CEACAM6 ...
    • Toxic heavy metal (Pb and Cd) content in tobacco cigarette brands in Selangor state, Peninsular Malaysia 

      Janaydeh M.; Ismail A.; Zulkifli S.Z.; Omar H. ( Springer International Publishing , 2019 , Article)
      Cadmium (Cd) and lead (Pb) are ubiquitous metals widely distributed in the environment, resulting in toxic health effects. This project aims to evaluate Pb and Cd as toxic elements in 15 different tobacco cigarette brands ...
    • Toxin stability improvement and toxicity increase against dipteran and lepidopteran larvae of Bacillus thuringiensis crystal protein Cry2Aa 

      Elleuch, Jihen; Jaoua, Samir; Ginibre, Carole; Chandre, Fabrice; Tounsi, Slim; ... more authors ( Wiley , 2016 , Article)
      BACKGROUND Bacillus thuringiensis δ-endotoxins are the most widely used biopesticides for controlling economically important crop pests and disease vectors. Improving their efficacy is of great benefit. Here, an improvement ...
    • Traditional plant functional groups explain variation in economic but not size-related traits across the tundra biome 

      Thomas, H. J. D.; Myers-Smith, I. H.; Bjorkman, A. D.; Elmendorf, S. C.; Blok, D.; ... more authors ( Wiley , 2019 , Article)
      Aim: Plant functional groups are widely used in community ecology and earth system modelling to describe trait variation within and across plant communities. However, this approach rests on the assumption that functional ...
    • TRAF6-mediated ubiquitination of NEMO requires p62/sequestosome-1 

      Zotti, Tiziana; Scudiero, Ivan; Settembre, Pio; Ferravante, Angela; Mazzone, Pellegrino; ... more authors ( Elsevier Ltd , 2014 , Article)
      The atypical protein kinase C-interacting protein p62/sequestosome-1 (p62) has emerged as a crucial molecule in a variety of cellular functions due to its involvement in various signaling mechanisms. p62 has been implicated ...
    • Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6 

      Hu, Yu-Jie; Belaghzal, Houda; Hsiao, Wen-Yu; Qi, Jun; Bradner, James E.; ... more authors ( Oxford University Press , 2015 , Article)
      Jumonji domain-containing protein 6 (JMJD6) is a nuclear protein involved in histone modification, transcription and RNA processing. Although JMJD6 is crucial for tissue development, the link between its molecular functions ...
    • Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling 

      de Oliveira, Ana Sofia Lima Estevao; Bloise, Giovanna; Moltrasio, Chiara; Coelho, Antonio; Agrelli, Almerinda; ... more authors ( MDPI , 2022 , Article)
      Hidradenitis suppurativa (HS) is an inflammatory skin condition clinically characterized by recurrent painful deep-seated nodules, abscesses, and sinus tracks in areas bearing apocrine glands, such as axillae, breasts, ...
    • Transient Receptor Potential Ankyrin 1 (TRPA1) Methylation and Chronic Pain: A Systematic Review 

      Celsi, Fulvio; Peri, Francesca; Cavasin, Julia; Zupin, Luisa; Cozzi, Giorgio; ... more authors ( MDPI , 2023 , Other)
      Background and Objective: Chronic pain represents a major global health issue in terms of psycho-physiological, therapeutic, and economic burden, not limited to adults but also to the pediatric age. Despite its great impact, ...
    • Treatment of Sand Using Microbial-Induced Carbonate Precipitation (MICP) for Wind Erosion Application 

      Gu J.; Suleiman M.T.; Bastola H.; Brown D.G.; Zouari N. ( American Society of Civil Engineers (ASCE) , 2018 , Conference Paper)
      Microbial-induced carbonate precipitation (MICP) has been used to improve soil properties for different geotechnical applications. This research focuses on evaluating the use of MICP for the wind erosion application. The ...
    • Tundra Trait Team: A database of plant traits spanning the tundra biome 

      Bjorkman A.D.; Myers-Smith I.H.; Elmendorf S.C.; Normand S.; Thomas H.J.D.; ... more authors ( Blackwell Publishing Ltd , 2018 , Article)
      Motivation: The Tundra Trait Team (TTT) database includes field-based measurements of key traits related to plant form and function at multiple sites across the tundra biome. This dataset can be used to address theoretical ...
    • Uncovering responses of zooplankton community to CO2 acidification in Qatar coastal waters 

      Ben-Hamadou, Radhouane; Aboshanab, Rawan; Sherif, Ahmed; Al-Mandili, Monzer; Omer, Ghadeer; ... more authors ( Hamad Bin Khalifa University Press , 2016 , Conference Paper)
      The combustion of fossil fuels is pushing atmospheric concentrations of carbon dioxide (CO2) to unprecedented levels. This rapid increase in atmospheric CO2 is causing global changes, with noticeable increases in temperature, ...
    • Uncovering responses of zooplankton community to CO2 acidification in Qatar cstal waters 

      Ben-Hamadou, Radhouane; Aboshanab, Rawan; Sherif, Ahmed; Al-Mandili, Monzer; Omer, Ghadeer; ... more authors ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)
      The combustion of fossil fuels is pushing atmospheric concentrations of carbon dioxide (CO2) to unprecedented levels. This rapid increase in atmospheric CO2 is causing global changes, with noticeable increases in temperature, ...