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SOD2, a Potential Transcriptional Target Underpinning CD44-Promoted Breast Cancer Progression
(
MDPI
, 2022 , Article Review)
CD44, a cell-adhesion molecule has a dual role in tumor growth and progression; it acts as a tumor suppressor as well as a tumor promoter. In our previous work, we developed a tetracycline-off regulated expression of CD44’s ...
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
(
Elsevier
, 2022 , Article Review)
Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ...
PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3'-End Polyadenylation Function to Tumor Cell Metastasis
(
Frontiers Media S.A.
, 2022 , Article Review)
Breast Cancer (BC) is the most common and the major health issue in women worldwide. Metastasis, a multistep process, is the worst aspect of cancer and tumor cell invasion is the defining step. Tumor cell invasion requires ...
Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis
(
Elsevier Ltd
, 2022 , Article Review)
Antibody-dependent enhancement (ADE) has been associated with severe disease outcomes in several viral infections, including respiratory infections. In vitro and in vivo studies showed that antibody-response to SARS-CoV ...