Browsing College of Medicine by Type "Article Review"

Now showing items 41-60 of 129

    • Early metabolic impairment as a contributor to neurodegenerative disease: Mechanisms and potential pharmacological intervention 

      Fakih, Walaa; Zeitoun, Ralph; AlZaim, Ibrahim; Eid, Ali H.; Kobeissy, Firas; ... more authors ( Wiley , 2022 , Article Review)
      The metabolic syndrome comprises a family of clinical and laboratory findings, including insulin resistance, hyperglycemia, hypertriglyceridemia, low high-density lipoprotein cholesterol levels, and hypertension, in addition ...

    • The effect of nuts consumption on circulating oxidized low-density lipoproteins: A systematic review and meta-analysis of randomized controlled trials. 

      Abbasifard, Mitra; Jamialahmadi, Tannaz; Reiner, Željko; Eid, Ali H; Sahebkar, Amirhossein ( Wiley , 2023 , Article Review)
      This systematic review and meta-analysis evaluated the effect of nuts in decreasing circulating levels of oxidized low-density lipoproteins (ox-LDL). A literature search was performed of major electronic databases ...

    • Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations. 

      Ramli, Iman; Posadino, Anna Maria; Giordo, Roberta; Fenu, Grazia; Fardoun, Manal; ... more authors ( MDPI , 2023 , Article Review)
      Adverse pregnancy outcomes are considered significant health risks for pregnant women and their offspring during pregnancy and throughout their lifespan. These outcomes lead to a perturbated in-utero environment that impacts ...

    • Effect of statins on abdominal aortic aneurysm 

      Azar, Hosseini; Sahranavard, Toktam; Reiner, Željko; Jamialahmadi, Tannaz; Dhaheri, Yusra Al; ... more authors ( Elsevier , 2022 , Article Review)
      Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth and rupture of aortic wall with a high death rate. Several studies have found that treatment with statins may decrease the progress ...

    • Emerging roles of activating transcription factor 2 in the development of breast cancer: a comprehensive review. 

      Amarah, Ahmed; Elsabagh, Ahmed Adel; Ouda, Amr; Karen, Omar; Ferih, Khaled; ... more authors ( Oxford University Press , 2023 , Article Review)
      Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins that are responsible for regulating various genes that play an essential role in major biological and cellular ...

    • Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression. 

      Cyprian, Farhan S; Al-Farsi, Halema F; Vranic, Semir; Akhtar, Saghir; Al Moustafa, Ala-Eddin ( Frontiers Media , 2018 , Article Review)
      Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein-Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, ...

    • Epstein-Barr Virus in Gliomas: Cause, Association, or Artifact? 

      Akhtar, Saghir; Vranic, Semir; Cyprian, Farhan Sachal; Al Moustafa, Ala-Eddin ( Frontiers Media , 2018 , Article Review)
      Gliomas are the most common malignant brain tumors and account for around 60% of all primary central nervous system cancers. Glioblastoma multiforme (GBM) is a grade IV glioma associated with a poor outcome despite recent ...

    • Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update. 

      Saleh, Alaaeldin; Kashir, Junaid; Thanassoulas, Angelos; Safieh-Garabedian, Bared; Lai, F Anthony; ... more authors ( Frontiers Media , 2020 , Article Review)
      Sperm-specific phospholipase C zeta (PLCζ) is widely considered to be the physiological stimulus responsible for generating calcium (Ca) oscillations that induce egg activation and early embryonic development during mammalian ...

    • Evolution of gastroesophageal reflux disease symptoms after bariatric surgery: A dose–response meta-analysis 

      Abdel-Naser, Elzouki; Waheed, Muhammad-Aamir; Suwileh, Salah; Elzouki, Islam; Swehli, Hisham; ... more authors ( Elsevier , 2022 , Article Review)
      BackgroundObesity is associated with increased prevalence of gastroesophageal reflux disease, with recent reports suggesting improvement in gastroesophageal reflux disease symptoms and weight loss following bariatric ...

    • Fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in castration-resistant prostate cancer cells: a potential therapeutic target 

      Naeem, Abdulghani A.; Abdulsamad, Saud A.; Rudland, Philip S.; Malki, Mohammed I.; Ke, Youqiang ( Oxford University Press , 2019 , Article Review)
      In this short communication, a novel fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in prostate cancer is reviewed. In castration-resistant prostate cancer (CRPC) cells, the FABP5-related signal ...

    • Five insights from the Global Burden of Disease Study 2019 

      Christopher J L, Murray; Abbafati, Cristiana; Abbas, Kaja M; Abbasi, Mohammad; Abbasi-Kangevari, Mohsen; ... more authors ( Elsevier , 2020 , Article Review)
      The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system ...

    • Follicular dendritic cells 

      Abd El-Aleem, Seham A; Saber, Entesar Ali; Aziz, Neven M; El-Sherif, Hani; Abdelraof, Asmaa M; ... more authors ( Wiley , 2021 , Article Review)
      Follicular dendritic cells (FDCs) are unique accessory immune cells that contribute to the regulation of humoral immunity. They are multitasker cells essential for the organization and maintenance of the lymphoid architecture, ...

    • Forging the Path to Precision Medicine in Qatar: A Public Health Perspective on Pharmacogenomics Initiatives 

      Bastaki, Kholoud; Velayutham, Dinesh; Irfan, Areeba; Adnan, Mohd; Mohammed, Sawsan; ... more authors ( Frontiers Media , 2024 , Article Review)
      Pharmacogenomics (PGx) is an important component of precision medicine that promises tailored treatment approaches based on an individual’s genetic information. Exploring the initiatives in research that help to integrate ...

    • Genetic risk factors in melanoma etiopathogenesis and the role of genetic counseling: A concise review. 

      Serman, Nikola; Vranic, Semir; Glibo, Mislav; Serman, Ljiljana; Bukvic Mokos, Zrinka ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2022 , Article Review)
      Melanoma is a highly aggressive cancer originating from melanocytes. Its etiopathogenesis is strongly related to genetic, epigenetic, and environmental factors. Melanomas encountered in clinical practice are predominantly ...

    • Giant parathyroid adenoma: A case report and review of the literature 

      Al-Hassan M.S.; Mekhaimar M.; El Ansari W.; Darweesh A.; Abdelaal A. ( BioMed Central Ltd. , 2019 , Article Review)
      Background: Giant parathyroid adenoma is a rare type of parathyroid adenoma defined as weighing > 3.5 g. They present as primary hyperparathyroidism but with more elevated laboratory findings and more severe clinical ...

    • Glycogen-rich Clear Cell Carcinoma of the Breast: A Comprehensive Review. 

      Vranic, Semir; Skenderi, Faruk; Beslagic, Vanesa; Gatalica, Zoran ( Lippincott, Williams & Wilkins , 2020 , Article Review)
      Glycogen-rich clear cell carcinoma (GRCC) is a very rare form of primary breast cancer (<0.1% of all breast cancers). It is characterized by the presence of neoplastic cells with a glycogen-abundant clear cytoplasm (the ...

    • Glycomic and Glycoproteomic Techniques in Neurodegenerative Disorders and Neurotrauma: Towards Personalized Markers 

      Kobeissy, Firas; Kobaisi, Abir; Peng, Wenjing; Barsa, Chloe; Goli, Mona; ... more authors ( MDPI , 2022 , Article Review)
      The proteome represents all the proteins expressed by a genome, a cell, a tissue, or an organism at any given time under defined physiological or pathological circumstances. Proteomic analysis has provided unparalleled ...

    • Gravitational Influence on Human Living Systems and the Evolution of Species on Earth 

      Adamopoulos, Konstantinos; Koutsouris, Dimitrios; Zaravinos, Apostolos; Lambrou, George I. ( MDPI , 2021 , Article Review)
      Gravity constituted the only constant environmental parameter, during the evolutionary period of living matter on Earth. However, whether gravity has affected the evolution of species, and its impact is still ongoing. The ...

    • Helicobacter pylori and epithelial mesenchymal transition in human gastric cancers: An update of the literature 

      Jamal Eddin, Tala M.; Nasr, Shahd M.O.; Gupta, Ishita; Zayed, Hatem; Al Moustafa, Ala-Eddin ( Elsevier , 2023 , Article Review)
      Gastric cancer, a multifactorial disease, is considered one of the most common malignancies worldwide. In addition to genetic and environmental risk factors, infectious agents, such as Epstein-Barr virus (EBV) and Helicobacter ...

    • Human antigen R: Exploring its inflammatory response impact and significance in cardiometabolic disorders 

      Abdelsam, Shahenda Salah; Ghanem, Sarah Khalaf; Zahid, Muhammad Ammar; Abunada, Hanan H.; Bader, Loulia; ... more authors ( Wiley , 2024 , Article Review)
      RNA-binding proteins (RBPs) play a crucial role in the regulation of posttranscriptional RNA networks, which can undergo dysregulation in many pathological conditions. Human antigen R (HuR) is a highly researched RBP that ...