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Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
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Elsevier B.V.
, 2017 , Article)
The critical role of α1-glycine receptor (α1-GLYRs) in pathological conditions such as epilepsy is well known. In the present study, structure-activity relations for a series of phenylalanine derivatives carrying selected ...
Clostridium difficile Infection and Risk of Colectomy in Patients with Inflammatory Bowel Disease: A Bias-adjusted Meta-analysis
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Wolters Kluwer
, 2017 , Article)
Clostridium difficile infection (CDI) is a common complication of inflammatory bowel diseases (IBDs) and is associated with worse outcome. Variable rates of colectomy have been reported among IBD complicated by CDI. We ...
Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs
(
Elsevier
, 2017 , Article)
PurposeThere are no published instruments, which measure tutor motivation for conducting small group tutorials in problem-based learning programs. Therefore, we aimed to develop a motivation for tutoring questionnaire in ...
Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an in vivo mouse model
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Hindawi Limited
, 2017 , Article)
Cigarette smoking (S) is a risk factor for progressive chronic kidney disease, renal dysfunction, and renal failure. In this study, the effect of smoking on kidney function was investigated in a mouse model of myocardial ...
Drug release kinetics from a drug-eluting stent with asymmetrical coat
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IMR Press Limited
, 2017 , Article)
The aim of this study was to investigate the drug release profiles of biodegradable polymer sirolimus- or paclitaxel-eluting stents with asymmetrical coating (BPSES-A or BPPES-A) both in vitro and in vivo. In vitro, the ...
Medical students' perceptions of supporting pharmacology learning in english by key information prepared in arabic
(
World Health Organization
, 2017 , Article)
We explored medical students' perceptions of supporting pharmacology self-learning in English by focused materials prepared in Arabic. This study targeted third-year medical students at the Arabian Gulf University in Bahrain ...
Implementation and evaluation of a patient safety course in a problem-based learning program
(2017 , Article)
Background: Since the development of the WHO patient safety curriculum guide, there has been insufficient reporting regarding the implementation and evaluation of patient safety courses in undergraduate problem-based ...
Continuity of sleep problems from adolescence to young adulthood: results from a longitudinal study
(
Elsevier Inc
, 2017 , Article)
Background
Considering the lack of evidence on incidence and continuity of sleep problems from adolescence to young adulthood, this study explores sleep problems’ incidence and their continuation rates from 14 to 21 ...
Thujone inhibits the function of 7-nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm
(
Elsevier Ireland Ltd
, 2017 , Article)
Effects of thujone, a major ingredient of absinthe, wormwood oil and some herbal medicines, were tested on the function of 7 subunit of the human nicotinic acetylcholine (7 nACh) receptor expressed in Xenopus oocytes using ...