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Novel whole-cell inactivated Neisseria gonorrhoeae microparticles as vaccine formulation in microneedle-based transdermal immunization
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MDPI AG
, 2018 , Article)
Neisseria gonorrhoeae is a strict human pathogen responsible for more than 100 million new sexually transmitted infections worldwide each year. Due to the global emergence of antibiotic resistance, the Center for Disease ...
Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center
(
American University of Beirut
, 2018 , Article)
Context: Blood transfusion services are critical to any hospitals? functioning, and timely blood/ component therapy resuscitation is lifesaving. Yet, few blood delivery turnaround time (TAT) studies have been undertaken. ...
The 4-hydroxynonenal mediated oxidative damage of blood proteins and lipids involves secondary lipid peroxidation reactions
(
Spandidos Publications
, 2018 , Article)
Lipid peroxidation is associated with several metabolic diseases. Lipid peroxidation causes cellular damage through reactive aldehyde species such as 4-hydroxyonenal (4-HNE). The exact mechanism(s) by which 4-HNE causes ...
Voltage dependence of the Ca2+ transient in endocardial and epicardial myocytes from the left ventricle of Goto Kakizaki type 2 diabetic rats
(
Springer New York LLC
, 2018 , Article)
Diabetes mellitus is a major global health disorder and, currently, over 450 million people have diabetes with 90% suffering from type 2 diabetes. Left untreated, diabetes may lead to cardiovascular diseases which are a ...
Signaling pathways activated by PACAP in MCF-7 breast cancer cells
(
Elsevier Inc.
, 2018 , Article)
PACAP has opposing roles ranging from activation to inhibition of tumor growth and PACAP agonists/antagonists could be used in tumor therapy. In this study, the effect of PACAP stimulation on signaling pathways was ...
Medical Education in Egypt: Historical Background, Current Status, and Challenges
(
Elsevier
, 2018 , Article)
BackgroundFrom its beginnings in 1827, an important goal of medical education in Egypt has been to qualify physicians who can provide high-quality health care services for their local community and other communities in the ...
Long Sun-Exposures Influencing High Sub-Cutaneous Synthesis of Vitamin-D3 may be Associated with Exacerbation of Symptoms in Allergic-Asthma.
(2018 , Article)
Does excessive sun-exposure, non-use of sunscreen and/or high doses of vitamin-D3 supplements provoke exacerbation of asthma? Clinical examinations, retrospective records-access and questionnaire surveys were distributed ...
Editorial: Role of Iron in Bacterial Pathogenesis
(
Frontiers Media S.A.
, 2018 , Article)
Iron is the fourth-most abundant element on the earth, and it is needed by most organisms, including bacteria. It exists in two oxidation states, Fe2+ and Fe3+, and is involved in many oxido-reduction reactions (Andrews ...
Perspectives and attitudes of jordanian medical and paramedical students toward surrogate pregnancy
(
Taylor & Francis Group
, 2018 , Article)
Purpose: This study aims at investigating the perspectives of Jordanian medical and paramedical students on surrogate pregnancy. Methods: A questionnaire-based cross-sectional study design was used. The sample consisted ...
Identification of FAM173B as a protein methyltransferase promoting chronic pain
(
Public Library of Science
, 2018 , Article)
Chronic pain is a debilitating problem, and insights in the neurobiology of chronic pain are needed for the development of novel pain therapies. A genome-wide association study implicated the 5p15.2 region in chronic ...