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TERT gene fusions characterize a subset of metastatic Leydig cell tumors
(
Elsevier
, 2021 , Article)
Objective: Metastatic Leydig cell tumors (LCT) are rare, difficult to treat malignancies without known underlying molecular-genetic events. An index case of metastatic LCT showed an LDLR-TERT gene fusion upon routine genetic ...
The Role of Pathology in the Era of Personalized (Precision) Medicine: A Brief Review.
(
NLM (Medline)
, 2021 , Article)
This review provides a brief overview of the state-of-the-art molecular pathology approaches emphasizing the increasingly important pathology role in clinical precision cancer medicine. Recent advances in molecular biology ...
Nutm1-rearranged neoplasms: A heterogeneous group of primitive tumors with expanding spectrum of histology and molecular alterations: An updated review
(
MDPI
, 2021 , Article)
Nuclear protein of testis (NUT), a protein product of the NUTM1 gene (located on the long arm of chromosome 15) with highly restricted physiologic expression in post-meiotic spermatids, is the oncogenic driver of a group ...
An Update on the Molecular and Clinical Characteristics of Apocrine Carcinoma of the Breast
(
Elsevier
, 2021 , Article)
Apocrine carcinoma of the breast is a rare malignancy. According to 2019 WHO classification, apocrine cellular features and a characteristic steroid receptor profile (Estrogen receptor (ER)-negative and androgen receptor ...